ID   M0PNE2_9EURY            Unreviewed;       302 AA.
AC   M0PNE2;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=DNA binding protein {ECO:0000313|EMBL:EMA71518.1};
GN   ORFNames=C462_06460 {ECO:0000313|EMBL:EMA71518.1};
OS   Halorubrum arcis JCM 13916.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum; Halorubrum distributum group.
OX   NCBI_TaxID=1230455 {ECO:0000313|EMBL:EMA71518.1, ECO:0000313|Proteomes:UP000011528};
RN   [1] {ECO:0000313|EMBL:EMA71518.1, ECO:0000313|Proteomes:UP000011528}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13916 {ECO:0000313|EMBL:EMA71518.1,
RC   ECO:0000313|Proteomes:UP000011528};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA71518.1}.
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DR   EMBL; AOJJ01000050; EMA71518.1; -; Genomic_DNA.
DR   RefSeq; WP_004596552.1; NZ_AOJJ01000050.1.
DR   AlphaFoldDB; M0PNE2; -.
DR   STRING; 1230455.C462_06460; -.
DR   PATRIC; fig|1230455.3.peg.1231; -.
DR   Proteomes; UP000011528; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR019293; ThiN.
DR   PANTHER; PTHR40730:SF3; TRANSCRIPTION REGULATOR THIR; 1.
DR   PANTHER; PTHR40730; TRANSCRIPTIONAL REGULATOR PROTEIN-LIKE PROTEIN; 1.
DR   Pfam; PF01381; HTH_3; 1.
DR   Pfam; PF10120; ThiP_synth; 1.
DR   SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
FT   DOMAIN          20..48
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50943"
SQ   SEQUENCE   302 AA;  31946 MW;  407324332CAF3C0C CRC64;
     MRFIEEVVVD EFLPTVRSML AEDLRDRGFT QSEVADALGI SQSAVSKYAA GDVARHEDIV
     DDERVRNLVE RVGEGLASGD LTPVAALVEI EVLIRQLEEG DLLADLHEAA MPALAEADVE
     FSVHDPDSGL RERERVLTSV RRGLRTLTNA SGFAGLIPNV GANVAECLAD AATVDDVAAV
     PGRLVDVKGR AMVPGEPEFG VSEHVATVLL AAREAGAPVR GAVNLRYDPE TVDTLAADHP
     TVEFDAERPT REAVADAVAA ADLPADGETL VLYQTGAVGI EPIVYVLAPT ASEAAAIVRE
     IL
//