ID M0PPM1_9EURY Unreviewed; 839 AA.
AC M0PPM1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=C462_04080 {ECO:0000313|EMBL:EMA71926.1};
OS Halorubrum arcis JCM 13916.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum; Halorubrum distributum group.
OX NCBI_TaxID=1230455 {ECO:0000313|EMBL:EMA71926.1, ECO:0000313|Proteomes:UP000011528};
RN [1] {ECO:0000313|EMBL:EMA71926.1, ECO:0000313|Proteomes:UP000011528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 13916 {ECO:0000313|EMBL:EMA71926.1,
RC ECO:0000313|Proteomes:UP000011528};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMA71926.1}.
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DR EMBL; AOJJ01000038; EMA71926.1; -; Genomic_DNA.
DR RefSeq; WP_007993866.1; NZ_AOJJ01000038.1.
DR AlphaFoldDB; M0PPM1; -.
DR STRING; 1230455.C462_04080; -.
DR PATRIC; fig|1230455.3.peg.755; -.
DR Proteomes; UP000011528; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 244..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 663..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 687..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 716..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 757..782
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 789..815
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 272..395
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 650..814
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 839 AA; 89086 MW; A916F0BC7BC4936F CRC64;
MSDSGAPVTA ADRLIEEIDR VVTERPLAVV AVFLLVTAGF AGGLTGIETS AGADQFTQDI
PAQRALDDID EEFETSIGGS ATSAQVIVSD DNVLSRDALV RTLETQHRLE SRSTLRVAST
SSHADAIARQ LDPDAANAAE RRDAVAEATP AELRTAIADA DAAGAIAAQV SVDYNPTAQA
ADTAIVGITY DLPDAATTAR VTELQTRSVE VVDSVPGNEA GENAILFGDG VLQSEITALL
TDTAIIVFPA ALILIVGFLI FAYRDPIDMA IGISALLISL LWTFGFMGYA GIPFSDSLVT
VFPLLLAVGI DFGIHIVNRY REERATGTGI EASMRTTTDQ LLIAFLLVTI TTVFGLVSNV
VSPFDPNRDF GIVAAAGITF TLVIFGVFLP AAKVLADRWR ERLPIPEFGT TALGSGGSRL
ARVLHVGVDL SRIAPVAVVA LLLVGGAVGG AYGTGVNTEF SEEAFFPDQD RLETYADLPE
PFAPTEYTFL DVLTLFEEEF EQDFVGSVTL YVDQSVRDDD ALELIDRTTR NPPDTFATTD
ERRAQATSIV TVIEDRAKRD PEFAALVERN DRLGNGVPDR NVDEVYDALL DSSAEGRARG
YVAADRGSAR IDYTIRPGVD NSEAVADVRA LAERTPLEAV PTGSLVVNEA VIDLLTESAI
RSLFAAFGLT ALFLALSYAY LEGKAVYGLL NLVPVLVTVG LLVGSMRLFE IPLTPINAPI
LSVSIGLGVD YTVHFVHRFV DEYQAGLPID EALDVTIAGT GGALTGSMLT TVSGLGVLWL
AVIPLLRDFG VLLALGVFYA YLCSILLVPS LVVVWDRYGG IVGLGLDDGL RESGAEGGR
//
