ID   M0PQA9_9EURY            Unreviewed;       541 AA.
AC   M0PQA9;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=PUA domain containing protein {ECO:0000313|EMBL:EMA72233.1};
DE   Flags: Fragment;
GN   ORFNames=C462_02769 {ECO:0000313|EMBL:EMA72233.1};
OS   Halorubrum arcis JCM 13916.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae; Halorubrum; Halorubrum distributum group.
OX   NCBI_TaxID=1230455 {ECO:0000313|EMBL:EMA72233.1, ECO:0000313|Proteomes:UP000011528};
RN   [1] {ECO:0000313|EMBL:EMA72233.1, ECO:0000313|Proteomes:UP000011528}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13916 {ECO:0000313|EMBL:EMA72233.1,
RC   ECO:0000313|Proteomes:UP000011528};
RX   PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA   Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA   Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT   "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT   strategies for static and dynamic osmo-response.";
RL   PLoS Genet. 10:E1004784-E1004784(2014).
CC   -!- PATHWAY: tRNA modification; archaeosine-tRNA biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00005030}.
CC   -!- SIMILARITY: Belongs to the archaeosine synthase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008906}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMA72233.1}.
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DR   EMBL; AOJJ01000031; EMA72233.1; -; Genomic_DNA.
DR   RefSeq; WP_007993457.1; NZ_AOJJ01000031.1.
DR   AlphaFoldDB; M0PQA9; -.
DR   UniPathway; UPA00393; -.
DR   Proteomes; UP000011528; Unassembled WGS sequence.
DR   GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR   CDD; cd21149; PUA_archaeosine_TGT; 1.
DR   Gene3D; 3.10.450.90; ArcTGT, C2 domain; 1.
DR   Gene3D; 2.30.130.10; PUA domain; 1.
DR   Gene3D; 3.20.20.105; Queuine tRNA-ribosyltransferase-like; 1.
DR   Gene3D; 3.40.50.10630; Uracil-DNA glycosylase-like; 1.
DR   InterPro; IPR040777; DUF5591.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR036511; TGT-like_sf.
DR   InterPro; IPR029402; TGT_C2.
DR   InterPro; IPR038250; TGT_C2_sf.
DR   InterPro; IPR002616; tRNA_ribo_trans-like.
DR   InterPro; IPR036895; Uracil-DNA_glycosylase-like_sf.
DR   NCBIfam; NF040592; tRNA_mod_ArcS; 1.
DR   PANTHER; PTHR46499:SF2; ARCHAEOSINE SYNTHASE; 1.
DR   PANTHER; PTHR46499; QUEUINE TRNA-RIBOSYLTRANSFERASE; 1.
DR   Pfam; PF17884; DUF5591; 1.
DR   Pfam; PF01472; PUA; 1.
DR   Pfam; PF01702; TGT; 1.
DR   Pfam; PF14810; TGT_C2; 1.
DR   SUPFAM; SSF88697; PUA domain-like; 1.
DR   SUPFAM; SSF51713; tRNA-guanine transglycosylase; 1.
DR   SUPFAM; SSF52141; Uracil-DNA glycosylase-like; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   3: Inferred from homology;
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          55..178
FT                   /note="tRNA-guanine(15) transglycosylase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01702"
FT   DOMAIN          222..374
FT                   /note="DUF5591"
FT                   /evidence="ECO:0000259|Pfam:PF17884"
FT   DOMAIN          388..482
FT                   /note="tRNA-guanine transglycosylase patch-forming"
FT                   /evidence="ECO:0000259|Pfam:PF14810"
FT   DOMAIN          496..540
FT                   /note="PUA"
FT                   /evidence="ECO:0000259|Pfam:PF01472"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EMA72233.1"
FT   NON_TER         541
FT                   /evidence="ECO:0000313|EMBL:EMA72233.1"
SQ   SEQUENCE   541 AA;  59349 MW;  9BAC8228D89CD9AD CRC64;
     RSFPAGTRDE VRESFAVEHP DAEFPSAAVV DSRSARDLGA DAYLLSDAEG FVGHGEAFRD
     AIVRAKESLP PDAALGLSGV ATPRNVAVLA YAGVDLVDET LARTKGTQGM YLTADAAHFL
     EDLDELPCAC PACAKSRSEF TRADCADHNA NALRAELRRV RERIRSGRLR DYIEAQARHE
     GWLTAAFREF DDQWGYVEER TPLMRDAEVT AASAETLDRV EIRRFADRVT SRYRNRFTDQ
     PLVLVPCSAT KPYSDSQSHR QFHDAIQWRG HTVSMTSPIG VVPQELETTY PAQHYDSVVT
     GDWSEDEIGF VAEVLRRYLE RNDYSRVIAH VPEDGYREIC ERVEGDPAVD VDFEYTCVDH
     PTTDESLGEL NAALQGEPAY SKREREHNTV RAIADYLLGD GAGDDLFGGR GAGGGDGVDI
     ERYGGEADVR TTGRYPKLQV WADDPDAGRE GEPGEQLATM VPQYGTLSFT LAGARRWVES
     DAPTKRVEID EFVPRGSVLA PGVVDAADEI RVGDEVVVEG PKAFAVGRAA MSGPEMAGAT
     R
//