ID M0R9X3_RAT Unreviewed; 565 AA.
AC M0R9X3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=RNA binding motif 31, Y-linked {ECO:0000313|Ensembl:ENSRNOP00000066307.1};
GN Name=Rbm31y {ECO:0000313|Ensembl:ENSRNOP00000066307.1,
GN ECO:0000313|RGD:1562219};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000066307.1, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000066307.1, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000066307.1,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0007829|PubMed:22673903}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
RN [3] {ECO:0000313|Ensembl:ENSRNOP00000066307.1}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000066307.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_001066404.1; XM_001066404.4.
DR RefSeq; XP_229073.1; XM_229073.4.
DR AlphaFoldDB; M0R9X3; -.
DR SMR; M0R9X3; -.
DR STRING; 10116.ENSRNOP00000066307; -.
DR iPTMnet; M0R9X3; -.
DR PhosphoSitePlus; M0R9X3; -.
DR jPOST; M0R9X3; -.
DR PaxDb; 10116-ENSRNOP00000066307; -.
DR Ensembl; ENSRNOT00000004491.6; ENSRNOP00000066307.1; ENSRNOG00000003377.6.
DR KEGG; rno:302780; -.
DR AGR; RGD:1562219; -.
DR CTD; 74484; -.
DR RGD; 1562219; Rbm31y.
DR eggNOG; KOG0118; Eukaryota.
DR GeneTree; ENSGT00940000154426; -.
DR HOGENOM; CLU_482287_0_0_1; -.
DR InParanoid; M0R9X3; -.
DR OMA; ANPNVYM; -.
DR OrthoDB; 5189206at2759; -.
DR Proteomes; UP000002494; Chromosome X.
DR Bgee; ENSRNOG00000003377; Expressed in testis.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR GO; GO:0034046; F:poly(G) binding; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR48033; RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN; 1.
DR PANTHER; PTHR48033:SF14; RNA-BINDING MOTIF 31, Y-LINKED; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF101967; Adhesin YadA, collagen-binding domain; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 1: Evidence at protein level;
KW Reference proteome {ECO:0000313|Proteomes:UP000002494};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 33..110
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 118..197
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 203..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 62292 MW; A746F49E3675EA09 CRC64;
MNTASLAVRK YNERDQLREG FRIDATKNQQ DASKMFIGGL SQELNKQVLL EYLSKFGEII
DFIIKIDPNT GLSRGFGFVL FKDSSTVEKV LRVKDHKVDG KKIEFKRAKA LESQFPIKKV
FVGGLNPRMS EEKIRAYFGT FGQIEAIELP LCSDTQERRA FGFIKYMDEN PVRKVLETRY
HFIGSSRCEV KMAFPKEYPA RQLSKSKTRA KDRARTAVPA AELENHWRGG GSQNFHIMDN
SDTQEANQDA HRAGSYTSRA NSDVTLSNAR GFRDTPNAFQ ANPNVIVTNS SAFRASRTAL
RPISNTVGLS HYALGANPNA FLANQYTFGA IPNALRTSQY TLGTYPNALG VSQYALAAYP
NAFGINQCTL GANPNVFWTN QYPLGTYPDA FGIGQYAWNM SPNVFGANQY TLGTNSDAFR
PNCYSFVANP YDIRTNHYVL ATNPNVSRTS QYILGANPNA FGSSHYSVGA SQNVFGPNQH
SFGVNGNFCG AAGSSGGTGG FNFSQVYGNF LNVCNTLPAF HGSNGDYFFL YSYGAYDVGS
APNYNVQINQ STLLGNGYQG IYSAF
//
