ID M0ZIE4_SOLTU Unreviewed; 360 AA.
AC M0ZIE4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Cinnamoyl-CoA reductase {ECO:0000313|EnsemblPlants:PGSC0003DMT400001401};
GN Name=102593519 {ECO:0000313|EnsemblPlants:PGSC0003DMT400001401};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400001401, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400001401}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400001401};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|RuleBase:RU004475}.
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DR RefSeq; XP_006338567.1; XM_006338505.2.
DR AlphaFoldDB; M0ZIE4; -.
DR STRING; 4113.M0ZIE4; -.
DR PaxDb; 4113-PGSC0003DMT400001401; -.
DR EnsemblPlants; PGSC0003DMT400001401; PGSC0003DMT400001401; PGSC0003DMG400000521.
DR GeneID; 102593519; -.
DR Gramene; PGSC0003DMT400001401; PGSC0003DMT400001401; PGSC0003DMG400000521.
DR KEGG; sot:102593519; -.
DR eggNOG; KOG1502; Eukaryota.
DR InParanoid; M0ZIE4; -.
DR OMA; ICFDQVI; -.
DR OrthoDB; 1215685at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF833; 3-BETA HYDROXYSTEROID DEHYDROGENASE_ISOMERASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU004475};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT DOMAIN 59..196
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 360 AA; 40298 MW; 4BF105D9CEAD2C54 CRC64;
MGIVCPDESK RIEIEEFRRM LLSNAAVHRT KAGDEFQNPG KLPAANRHNR ELEEKKVCVT
SGVSFLGIAI VNQLLLRGYS VRVIVEKQED LEKLREMEIS GEMRQSMNTV EAVMARLNDI
QSLSQAFSGC RGVFHTAAFV DPAGLSGYSK SMVEVEVLVT KNVTQACAIT PSVRNCVLTS
SLVACVWQDI NSSRTIDHDC WSDESICIDK KLWYALGKLK AERVAWNIAR ESGFKLATIC
PGLLTGPEFI SRNPTPTIAY LKGAQEMFRN GLLATVDVNR LAVEHVLVFE DMKNTSYNRY
ISFDQVIRSE EELEKLARET GIDIRTTRSN SRTNSSNIVK LSNAKLCGLM STIHRCHNEF
//
