ID   M1AGR2_SOLTU            Unreviewed;       309 AA.
AC   M1AGR2;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   08-NOV-2023, entry version 41.
DE   SubName: Full=Aspartic proteinase nepenthesin-1 {ECO:0000313|EnsemblPlants:PGSC0003DMT400022457};
GN   Name=102583826 {ECO:0000313|EnsemblPlants:PGSC0003DMT400022457};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400022457, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400022457}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400022457};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family.
CC       {ECO:0000256|ARBA:ARBA00007447}.
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DR   AlphaFoldDB; M1AGR2; -.
DR   EnsemblPlants; PGSC0003DMT400022457; PGSC0003DMT400022457; PGSC0003DMG400008703.
DR   Gramene; PGSC0003DMT400022457; PGSC0003DMT400022457; PGSC0003DMG400008703.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; M1AGR2; baseline and differential.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.40.70.10; Acid Proteases; 2.
DR   InterPro; IPR001461; Aspartic_peptidase_A1.
DR   InterPro; IPR001969; Aspartic_peptidase_AS.
DR   InterPro; IPR033121; PEPTIDASE_A1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR032799; TAXi_C.
DR   InterPro; IPR032861; TAXi_N.
DR   PANTHER; PTHR13683:SF743; ASPARTIC PROTEINASE-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR13683; ASPARTYL PROTEASES; 1.
DR   Pfam; PF14541; TAXi_C; 1.
DR   Pfam; PF14543; TAXi_N; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   PROSITE; PS00141; ASP_PROTEASE; 1.
DR   PROSITE; PS51767; PEPTIDASE_A1; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT   DOMAIN          1..309
FT                   /note="Peptidase A1"
FT                   /evidence="ECO:0000259|PROSITE:PS51767"
SQ   SEQUENCE   309 AA;  33517 MW;  2BD47C812B9A0193 CRC64;
     MFLFSLHWML EVTCCGFRVN VYNALLFQPV IIAAWCSLVF GASIMQDKDL NEYNPSGSST
     SKFLSCSHQL CELGSNCKNP KQPCPYTVNY VSEDTSTSGV LVEDILHLAS GNRMAANGSA
     RAPVTFGCGS KQTGGYLNGV APDGLMGLGP GEISVPSRLA KAGLVRNSFS LCFKEDDSGR
     IFFGDQGPAG QQTTSFLPSE GQFVTYVVGV ESCCFGSSCI EQTSFKAIVD SGSSFTFLPD
     QIYDRVVKEF DRKVNATKAS FEGYPWQYCY KSSSEVLPKI PSFTLKFTAN SSFIVQDPVF
     MIYGSQVSA
//