ID   M1APS6_SOLTU            Unreviewed;       883 AA.
AC   M1APS6;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=HJTR2GH1 protein {ECO:0000313|EnsemblPlants:PGSC0003DMT400027529};
GN   Name=102587953 {ECO:0000313|EnsemblPlants:PGSC0003DMT400027529};
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400027529, ECO:0000313|Proteomes:UP000011115};
RN   [1] {ECO:0000313|Proteomes:UP000011115}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX   PubMed=21743474; DOI=10.1038/nature10158;
RG   The Potato Genome Sequencing Consortium;
RT   "Genome sequence and analysis of the tuber crop potato.";
RL   Nature 475:189-195(2011).
RN   [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400027529}
RP   IDENTIFICATION.
RC   STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400027529};
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   RefSeq; XP_006356854.1; XM_006356792.2.
DR   AlphaFoldDB; M1APS6; -.
DR   PaxDb; 4113-PGSC0003DMT400027529; -.
DR   EnsemblPlants; PGSC0003DMT400027529; PGSC0003DMT400027529; PGSC0003DMG400010612.
DR   GeneID; 102587953; -.
DR   Gramene; PGSC0003DMT400027529; PGSC0003DMT400027529; PGSC0003DMG400010612.
DR   KEGG; sot:102587953; -.
DR   eggNOG; KOG4658; Eukaryota.
DR   HOGENOM; CLU_000837_25_4_1; -.
DR   InParanoid; M1APS6; -.
DR   OMA; CICQKEA; -.
DR   OrthoDB; 346769at2759; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1193; DISEASE RESISTANCE PROTEIN RPP13-RELATED; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011115}.
FT   DOMAIN          5..87
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          180..425
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   883 AA;  101781 MW;  BB282F91BC2B259F CRC64;
     MVDAVVSYAV EKLGTFLIEE VSLRQSLREN VLWLRNELSF MKAFLKDAEK NQEQDNLVQQ
     WVFEITSVAN DAVYILEAYS LDAAKDGDHA AGFVDRLKAY ACICQKEAKL HDIGKDIQSL
     KERVMDISRK RDTYGIAHNN SNAGEGPSNR PNYTSSMLTL RRAVSYADED QLFVGFQEVF
     QRLLDELLKE ESHRKVLSIY GMGGLGKTTL ARNLYNSPSL ITTFHTRAWI SVSQQYSIPD
     LLRSIIKSIE GCSEELLKLL KEMSERDLET YLRNLLKKHK YLVVVDDVWH REAWESLQRA
     LPDDNNGSRV ILTTRKKEVA ERVDDKGFPH ELRFLNKKES WDLLCKKLHP ENKMVGADLY
     SPSMERLANE MVEKCGGLPL AIVVLGGILS YRKGVDEWQK VKTHLWQHMK NDSVEITHIL
     SLSYNDLSFE LKQCFLYIGI FQEDHVIDTE KLMHLWLAEG FIPRIREEHM EDIAENFLHE
     LISRSLIQVA ETFFDKFFAC KIHDLLRDLA VQKSMEVNLF DIYDPSVSSV TPFRHRHAIH
     GQTQKYLSLD LSKLKVRSIL FFDKEFEKLD NSEKFMTFCT TFPHLYVLDL ENIYFSEGKL
     PDAIGNLVHL KFLGLSNTNL FKLPSSIAKL ENLQTLEALI DDYCSCQLPP QIAKLTNLRH
     LITRYEVPLQ VNRLTNLRTL KYIRCDQWKD TDASGLVNLQ ELGMEQIAKS YSLISIGNLK
     SLTTLFLICN RGGTFPPLEP LSSCENLHRL WLSGGIEELA NLNNLPKSIT VLVLQSPFYT
     GLEEDPMPIL GKFPNLKHLE LSCAYMGKKI TCNGNSFGQL ETLRLEYLDN LESWHLHTTA
     MSVLKSLSIR QCPKLMKIPK RMEHIKMLDG NQSQREYYYR FPH
//