ID M1B7C9_SOLTU Unreviewed; 529 AA.
AC M1B7C9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN Name=102578456 {ECO:0000313|EnsemblPlants:PGSC0003DMT400038784};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400038784, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400038784}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400038784};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR RefSeq; XP_006355403.1; XM_006355341.2.
DR RefSeq; XP_006355404.1; XM_006355342.2.
DR RefSeq; XP_015167827.1; XM_015312341.1.
DR RefSeq; XP_015167828.1; XM_015312342.1.
DR AlphaFoldDB; M1B7C9; -.
DR SMR; M1B7C9; -.
DR STRING; 4113.M1B7C9; -.
DR PaxDb; 4113-PGSC0003DMT400038784; -.
DR EnsemblPlants; PGSC0003DMT400038784; PGSC0003DMT400038784; PGSC0003DMG400014989.
DR EnsemblPlants; PGSC0003DMT400038785; PGSC0003DMT400038785; PGSC0003DMG400014989.
DR GeneID; 102578456; -.
DR Gramene; PGSC0003DMT400038784; PGSC0003DMT400038784; PGSC0003DMG400014989.
DR Gramene; PGSC0003DMT400038785; PGSC0003DMT400038785; PGSC0003DMG400014989.
DR Gramene; RHC01H1G2022.2.1; RHC01H1G2022.2.1; RHC01H1G2022.2.
DR KEGG; sot:102578456; -.
DR eggNOG; KOG0166; Eukaryota.
DR HOGENOM; CLU_018084_5_0_1; -.
DR InParanoid; M1B7C9; -.
DR OMA; NWSTISV; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR GO; GO:0006607; P:NLS-bearing protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 5.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..58
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 117..160
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 160..202
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 244..286
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 328..371
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 371..399
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 529 AA; 58651 MW; 61C91AEBAF1F2B3A CRC64;
MSLRPSDRTE VRRNRYKVAV DADEGRRRRE DNLVEIRKSK REESLLKKRR EGLQAQQQQF
PANLQTSTVE KKLESLPSMV AGVWSNDNNM QLEATTQFRK LLSIERSPPI EEVIQSGVVP
RFVEFLMRED FPQLQFEAAW ALTNIASGTS ENTRVVIDHG AVPIFVKLLA SPSDDVREQA
VWALGNVAGD SPRCRDLVLS NGALIPLLSQ LNEHAKLSML RNATWTLSNF CRGKPQPPFE
QVRPALSALQ RLVHSNDEEV LTDACWALSY LSDGTNDKIQ AVIEAGVCPR LVELLMHPSP
SVLIPALRTV GNIVTGDDLQ TQCIIEHGAL ACLLSLLSHS HKKSIKKEAC WTISNITAGN
KEQIQAVVEA GLISPLVNLL QTAEFDIKKE AAWAISNATS GGSHEQIKFL VSQNCIKPLC
DLLVCPDPRI VTVCLEGLEN ILKVGEAEKA NTEGINYYAQ LIDDAEGLEK IENLQSHDNN
EIYEKAVKIL ETYWLEEEDE TVPAGDGAQN EFNFGGNDIQ LPSGGFKFG
//
