ID M1CWG4_SOLTU Unreviewed; 1230 AA.
AC M1CWG4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Leucine-rich repeat receptor protein kinase EXS {ECO:0000313|EnsemblPlants:PGSC0003DMT400076250};
GN Name=102591961 {ECO:0000313|EnsemblPlants:PGSC0003DMT400076250};
OS Solanum tuberosum (Potato).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113 {ECO:0000313|EnsemblPlants:PGSC0003DMT400076250, ECO:0000313|Proteomes:UP000011115};
RN [1] {ECO:0000313|Proteomes:UP000011115}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DM1-3 516 R44 {ECO:0000313|Proteomes:UP000011115};
RX PubMed=21743474; DOI=10.1038/nature10158;
RG The Potato Genome Sequencing Consortium;
RT "Genome sequence and analysis of the tuber crop potato.";
RL Nature 475:189-195(2011).
RN [2] {ECO:0000313|EnsemblPlants:PGSC0003DMT400076250}
RP IDENTIFICATION.
RC STRAIN=DM1-3 516 R44 {ECO:0000313|EnsemblPlants:PGSC0003DMT400076250};
RG EnsemblPlants;
RL Submitted (JUN-2015) to UniProtKB.
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DR RefSeq; XP_006360370.2; XM_006360308.2.
DR AlphaFoldDB; M1CWG4; -.
DR STRING; 4113.M1CWG4; -.
DR PaxDb; 4113-PGSC0003DMT400076250; -.
DR EnsemblPlants; PGSC0003DMT400076250; PGSC0003DMT400076250; PGSC0003DMG400029644.
DR GeneID; 102591961; -.
DR Gramene; PGSC0003DMT400076250; PGSC0003DMT400076250; PGSC0003DMG400029644.
DR KEGG; sot:102591961; -.
DR eggNOG; ENOG502QQEU; Eukaryota.
DR HOGENOM; CLU_000288_22_1_1; -.
DR InParanoid; M1CWG4; -.
DR OMA; NRDSCFL; -.
DR OrthoDB; 460040at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR45974:SF283; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45974; RECEPTOR-LIKE PROTEIN 55; 1.
DR Pfam; PF00560; LRR_1; 10.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51450; LRR; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000011115};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1230
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004013545"
FT TRANSMEM 707..728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 767..1054
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1067..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1170..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 796
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1230 AA; 133294 MW; B114212F372041F8 CRC64;
MSSSSSNPNK KYHFFLFLVT LFFTSSSSSA AVTDVVAPFS NWDILDDTPC KWSFIKCNFQ
GFITEINIQS IHLELPLPTN LSSYKYLKKL VISDANITGT IPFNIGDCSS LVTIDLSSNG
LVGTIPLSIG TLVNLQDLIL NSNQLTGRIP VEIGNCRNLK NLVLFDNRLS GGLPSEIGLL
SNLEVLRAGG NKDVTGKIPN EFGDCGNLTV LGLADTRISG SLPVSLGKLK NLETLSIYTT
MLSGEIPSDL GNCTELVNLY LYENSLSGSI PSELGNLRKL EKLLLWQNNL VGVIPEEIGN
CTKLTMIDLS LNYLSGSIPL SFGGLVVLQE LMLSNNNVSG SIPSVLSQCT SLVQLQFDTN
QISGLIPSEL GNLTSLVVFF AWDNQLEGSV PLTLGSCSNL QALDLSHNSL TGSIPPGLFQ
LKNLTKLLLI SNDISGTIPR EIGYCSSLVR LRLGNNRIAG GIPKEIGGLK SLNFLDLSGN
RLSGPVPDEI NSCTELQMVD LSSNTLEGPL PNTLSSLSGI QVLDVSNNRF GGPISASFGR
LVSLNKLILS KNSFSGSIPP SIGLCSSLQL LDLSSNELSG GIPMQLGKIE SLEITLNLSF
NELTGPIPAE ISSLSKLSIL DLSHNKLEGN LNPLARLDNL VSLNVSYNNF TGYLPDNKLF
RQLPSSDLDG NEGLCSFGRP SCFLSNIDGV GVAKNGNDEG RSKKLKLAIA LLVIMTIAMV
IMGTIAIIRA RRAMRRDDDS EMGDSWAWQF TPFQKLNFSV DEILRCLVDT NVIGKGCSGM
VYRADMNNGD VIAVKKLWPI TMTTTNGGND EKCGVRDSFS AEVKTLGSIR HKNIVRFLGC
CWNRSTRLLM YDYMPNGSLG SLLHERGGNP LEWELRYQIL LGAAQGLAYL HHDCAPPIVH
RDIKANNILI GLEFEPYIAD FGLAKLVDDG DFGRSSNTVA GSYGYIAPEY GYMMKITAKS
DVYSYGVVVL EVLTGKQPID PTIPEGVHLV DWVRRKRGGI EVLDPSLHSR PESEIEEMLQ
ALGVALLCVN STPDERPTMK DVAAMLKEIK HEREEYAKVD VLLKGSPTTT TTTDHNQENN
NSSKGVLATS SSGQKARSMY TMSNNTSFSA SSLLYYSSSS SNAKSRFLGC CWNRSTRLLM
YDYMPNGSLG SLLHEREEYA KVDVLLKGSP TTTTTTDHNQ ENNNSSKGVL ATSSSGQKAR
SMYTMSNNTS FSASSLLYYS SSSSNAKSGV
//
