ID M1ECF5_MUSPF Unreviewed; 527 AA.
AC M1ECF5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=CD166 antigen {ECO:0000256|ARBA:ARBA00015291};
DE AltName: Full=Activated leukocyte cell adhesion molecule {ECO:0000256|ARBA:ARBA00030009};
DE Flags: Fragment;
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|EMBL:AER94014.1};
RN [1] {ECO:0000313|EMBL:AER94014.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Lungs {ECO:0000313|EMBL:AER94014.1};
RX PubMed=23236062; DOI=10.1128/JVI.02476-12;
RA Leon A.J., Banner D., Xu L., Ran L., Peng Z., Yi K., Chen C., Xu F.,
RA Huang J., Zhao Z., Lin Z., Huang S.H., Fang Y., Kelvin A.A., Ross T.M.,
RA Farooqui A., Kelvin D.J.;
RT "Sequencing, annotation, and characterization of the influenza ferret
RT infectome.";
RL J. Virol. 87:1957-1966(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection,
CC dendrite {ECO:0000256|ARBA:ARBA00004279}.
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DR EMBL; JP005417; AER94014.1; -; mRNA.
DR AlphaFoldDB; M1ECF5; -.
DR HOGENOM; CLU_028888_2_0_1; -.
DR GO; GO:0030424; C:axon; IEA:UniProtKB-SubCell.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11973:SF2; CD166 ANTIGEN; 1.
DR PANTHER; PTHR11973; CELL SURFACE GLYCOPROTEIN MUC18-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 472..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..178
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 189..272
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 291..353
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 360..445
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AER94014.1"
FT NON_TER 527
FT /evidence="ECO:0000313|EMBL:AER94014.1"
SQ SEQUENCE 527 AA; 58800 MW; 40D9D79A22F67150 CRC64;
KYEKPDGSPV FIAFRSSTKK SVQYDDVPEY RDRLSLSENY TLSISNARIS DEKRFVCMLV
TEDNVFEAPT IVKVFKQPSK PEIVSQAPFL ETEQLKKLGD CISKDSYPDG NITWYRNGKV
LQPLEGVVVL IFKKQMDPVT QLYTMTSSLE YKATKADIQM PFTCSVTYYG PSGQKTLQSE
QAIFDIYYPT EQVTIQVLPS KNAIKEGDNI TLKCLGNGNP PPEEFLFYLP GQPEGIRSSN
TYTLTDVRRN ATGDYRCSLI DKKSMIASTA ITVHYLDLSL NPSGEVTKQI GDALPVSCTI
SASRNATVVW MKDNIRLRSS PSFSSLHYQD AGNYVCETAL QDVEGLKKRE SLTLIVEGKP
QIKMTKKTDP SGLSKTIICH VEGFPKPAIQ WTITGSGSVI NQTEESPYIN GRYYSKIIIS
PEENVTLTCT AENQLERTVN SLNVSAISIP EHDEADEISD ENREKVNDQA KLIVGIVVGL
LLAALVAGVV YWLYMKKSKT ASKHVNKDLG NLEENKKLEE NNHKTEA
//
