ID M1HD38_9PHYC Unreviewed; 314 AA.
AC M1HD38;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 13-SEP-2023, entry version 26.
DE SubName: Full=GIY-YIG catalytic domain-containing endonuclease {ECO:0000313|EMBL:AGE49697.1};
GN Name=Can18-4_056L {ECO:0000313|EMBL:AGE49697.1};
GN ORFNames=PBCVCan184_056L {ECO:0000313|EMBL:AGE49697.1};
OS Paramecium bursaria Chlorella virus Can18-4.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Algavirales; Phycodnaviridae; Chlorovirus.
OX NCBI_TaxID=1278252 {ECO:0000313|EMBL:AGE49697.1, ECO:0000313|Proteomes:UP000246183};
RN [1] {ECO:0000313|EMBL:AGE49697.1, ECO:0000313|Proteomes:UP000246183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Jeanniard A., Dunigan D.D., Gurnon J.R., Agarkova I., Kang M., Vitek J.,
RA Duncan G., McClung O.W., Larsen M., Claverie J.-M., Van Etten J.L.,
RA Blanc G.;
RT "Towards defining the chloroviruses: a genomic journey through a genus of
RT large DNA viruses.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: To endonucleases of group I introns of fungi and phage.
CC {ECO:0000256|ARBA:ARBA00010045}.
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DR EMBL; JX997157; AGE49697.1; -; Genomic_DNA.
DR Proteomes; UP000246183; Genome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd10443; GIY-YIG_HE_Tlr8p_PBC-V_like; 1.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR006350; Intron_endoG1.
DR InterPro; IPR003647; Intron_nuc_1_rpt.
DR InterPro; IPR003611; NUMOD3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR01453; grpIintron_endo; 2.
DR Pfam; PF07460; NUMOD3; 7.
DR SMART; SM00465; GIYc; 1.
DR SMART; SM00497; IENR1; 1.
DR SMART; SM00496; IENR2; 7.
DR SUPFAM; SSF64496; DNA-binding domain of intron-encoded endonucleases; 4.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:AGE49697.1};
KW Hydrolase {ECO:0000313|EMBL:AGE49697.1};
KW Nuclease {ECO:0000313|EMBL:AGE49697.1}.
FT DOMAIN 1..90
FT /note="GIY-YIG"
FT /evidence="ECO:0000259|SMART:SM00465"
FT DOMAIN 92..108
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT DOMAIN 116..132
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT DOMAIN 133..149
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT DOMAIN 157..173
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT DOMAIN 181..197
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT DOMAIN 205..221
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT DOMAIN 229..245
FT /note="Nuclease associated modular"
FT /evidence="ECO:0000259|SMART:SM00496"
FT REGION 87..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 35358 MW; 043F9A6051D732B0 CRC64;
MGFIYKATYR VSRKAYIGQT IQPIEKRLLQ HQYPSSKCRA FLGAIKKYGW ENFDVDWYEC
PDEDLNDLEE YLVAVLGTLA PGGYNLKEGG GAHGKPSVET REKMSEAHKG EKNHMYGKTL
SKETKQKLSE AHTGKTLSKE TKQKMSEALS GEKHPMFGKT LSKETKQKIS EALSGEKSHM
FGKTLSKETK QKISEALSGE KCYMYGKTLS KETKQKMSES TKGENNHFYG KTHAKETKEK
ISAAKTGAKN PRSKKVYRYE LNGTFVDYFG SSGEAARHVM SSEENEGSVK ASIGKCARGE
REYVHGFKWS YTKL
//
