ID M1MJP8_9CLOT Unreviewed; 431 AA.
AC M1MJP8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Uracil permease UraA {ECO:0000313|EMBL:AGF56538.1};
GN Name=uraA {ECO:0000313|EMBL:AGF56538.1};
GN ORFNames=Cspa_c27750 {ECO:0000313|EMBL:AGF56538.1};
OS Clostridium saccharoperbutylacetonicum N1-4(HMT).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=931276 {ECO:0000313|EMBL:AGF56538.1, ECO:0000313|Proteomes:UP000011728};
RN [1] {ECO:0000313|EMBL:AGF56538.1, ECO:0000313|Proteomes:UP000011728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N1-4(HMT) {ECO:0000313|Proteomes:UP000011728};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium saccharoperbutylacetonicum N1-4(HMT).";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CP004121; AGF56538.1; -; Genomic_DNA.
DR RefSeq; WP_015392857.1; NZ_AOIF01000096.1.
DR AlphaFoldDB; M1MJP8; -.
DR STRING; 36745.CLSAP_25280; -.
DR KEGG; csr:Cspa_c27750; -.
DR PATRIC; fig|931276.5.peg.2789; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_1_2_9; -.
DR OrthoDB; 9779092at2; -.
DR Proteomes; UP000011728; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011728};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..366
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 431 AA; 45734 MW; 698572BEC9C3B7CA CRC64;
MTTNELYENT NDFVDVTEKI PLKRAIPLSF QHLFAMFGSS VLVPLIFKID PTTVLFFNGI
GTLLYAFLTK KKIPAYLGSS FAFISPVLLL YSQGYNFETI QGGFVAAGVV FSIIAIIVGY
TGIGWVDKLF PPAAMGAIIT IIGLELASTA ADMAGFPVGG SNTQTLNVSW VIVSSITLVT
VILCNVLLRG FLKLIPILIG VVVGYIVSLS MGLIDFSTVS NASFFLLPNI KVAHFDINAI
LTILPATFVV IAEHVGHLKV TSSIVGKDLT KDPGLHRSLL GDGLSTIISG MFGSVPTTTY
GENIGVLALT KVYSVYVICG AGLISIILGF SGKMSAIIST IPTPVIGGVS LLLFGSIATS
GLRTFIEGKV DFSKSRNLIL TSIIFVIGLS GIKLTFGSTE IKGMGLATLV AMVLSISFMI
FDKLGIMNEK E
//
