ID   M1N0R3_9CORY            Unreviewed;       493 AA.
AC   M1N0R3;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 49.
DE   SubName: Full=Cardiolipin synthase {ECO:0000313|EMBL:AGF73489.1};
GN   ORFNames=A605_12465 {ECO:0000313|EMBL:AGF73489.1};
OS   Corynebacterium halotolerans YIM 70093 = DSM 44683.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1121362 {ECO:0000313|EMBL:AGF73489.1, ECO:0000313|Proteomes:UP000011723};
RN   [1] {ECO:0000313|EMBL:AGF73489.1, ECO:0000313|Proteomes:UP000011723}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIM 70093 {ECO:0000313|EMBL:AGF73489.1};
RX   PubMed=23408721;
RA   Ruckert C., Albersmeier A., Al-Dilaimi A., Niehaus K., Szczepanowski R.,
RA   Kalinowski J.;
RT   "Genome sequence of the halotolerant bacterium Corynebacterium halotolerans
RT   type strain YIM 70093(T) (= DSM 44683(T)).";
RL   Stand. Genomic Sci. 7:284-293(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003697; AGF73489.1; -; Genomic_DNA.
DR   RefSeq; WP_015401904.1; NZ_JIAJ01000006.1.
DR   AlphaFoldDB; M1N0R3; -.
DR   STRING; 1121362.A605_12465; -.
DR   KEGG; chn:A605_12465; -.
DR   PATRIC; fig|1121362.3.peg.2532; -.
DR   eggNOG; COG1502; Bacteria.
DR   HOGENOM; CLU_038053_1_0_11; -.
DR   OrthoDB; 9762009at2; -.
DR   Proteomes; UP000011723; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR022924; Cardiolipin_synthase.
DR   InterPro; IPR027379; CLS_N.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 2.
DR   Pfam; PF13396; PLDc_N; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW   Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        41..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          219..246
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          400..433
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   493 AA;  56280 MW;  E59A4653ABC78A2B CRC64;
     MSLSLDLSTW QFIGLLIDYT IKILAIGFVP EGRRPSSSTA WLLAILLLPY VGLPLFLLMG
     SPYINRRRHR IQQEANVMIE DVHSHIPDQP RGMDLNPTVE STIRLNRRLT NLPAVYAHNL
     GLHNDYNQAI RRMAEAIDEA REYVSVEIYI MAWDDTTEVF FHALERAVQR GVKVRLLFDQ
     VGSWKYPGYL KLGRRLTRIG VDWHLMLPLK PWRARFRRPD LRNHRKLVIV DGEIGFMGSL
     NLIDRSYLLR GHRRAGRKWV DSLVELSGPV VASLELVFAV DWYTESGETI DLAPPAVDTG
     GTENTNIVQF VPSGPGYTTE PNLRMFNSII HHAKERLMLC SPYFIPDEAL LDAVTTACYR
     GVRVELLVSE QSDQFMVHHA QSSYYQALLE AGVHIYLFPS PYVLHTKFML ADPDGEGDQA
     VGAYGSANMD IRSFGLNYES TMMIAHGNLL DQLNELGGIY RSVSRQLTLE EWNRRGFFRR
     YIDNVMKLTS ALQ
//