ID M1Q8G9_METMZ Unreviewed; 217 AA.
AC M1Q8G9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Iron-dependent repressor IdeR/DtxR {ECO:0000313|EMBL:AGF96453.1};
GN ORFNames=MmTuc01_1060 {ECO:0000313|EMBL:AGF96453.1};
OS Methanosarcina mazei Tuc01.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX NCBI_TaxID=1236903 {ECO:0000313|EMBL:AGF96453.1, ECO:0000313|Proteomes:UP000011718};
RN [1] {ECO:0000313|EMBL:AGF96453.1, ECO:0000313|Proteomes:UP000011718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuc01 {ECO:0000313|EMBL:AGF96453.1,
RC ECO:0000313|Proteomes:UP000011718};
RX PubMed=23704185;
RA Assis das Gracas D., Thiago Juca Ramos R., Vieira Araujo A.C., Zahlouth R.,
RA Ribeiro Carneiro A., Souza Lopes T., Azevedo Barauna R., Azevedo V.,
RA Cruz Schneider M.P., Pellizari V.H., Silva A.;
RT "Complete Genome of a Methanosarcina mazei Strain Isolated from Sediment
RT Samples from an Amazonian Flooded Area.";
RL Genome Announc. 1:E00271-13(2013).
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DtxR/MntR family.
CC {ECO:0000256|ARBA:ARBA00007871}.
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DR EMBL; CP004144; AGF96453.1; -; Genomic_DNA.
DR RefSeq; WP_011032983.1; NC_020389.1.
DR AlphaFoldDB; M1Q8G9; -.
DR GeneID; 82160059; -.
DR KEGG; mmaz:MmTuc01_1060; -.
DR HOGENOM; CLU_069532_0_2_2; -.
DR BioCyc; MMAZ1236903:G139K-1008-MONOMER; -.
DR Proteomes; UP000011718; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR Gene3D; 2.30.30.90; -; 1.
DR Gene3D; 1.10.60.10; Iron dependent repressor, metal binding and dimerisation domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR007167; Fe-transptr_FeoA.
DR InterPro; IPR001367; Fe_dep_repressor.
DR InterPro; IPR036421; Fe_dep_repressor_sf.
DR InterPro; IPR038157; FeoA_core_dom.
DR InterPro; IPR022687; HTH_DTXR.
DR InterPro; IPR022689; Iron_dep_repressor.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR Pfam; PF02742; Fe_dep_repr_C; 1.
DR Pfam; PF01325; Fe_dep_repress; 1.
DR Pfam; PF04023; FeoA; 1.
DR SMART; SM00899; FeoA; 1.
DR SMART; SM00529; HTH_DTXR; 1.
DR SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50944; HTH_DTXR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..64
FT /note="HTH dtxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50944"
SQ SEQUENCE 217 AA; 24627 MW; 7CED7DED29A7E29B CRC64;
MHTDRLEEYL ETILYLITKN QSPAKTKQIA EELNVSSPSV TEMIKKLHSM GFVEYKPYQG
VELTEKGAEE AVRIKRKHQV LETFLAEVLD FDRREAHKEA CELEHAVSDS VLERIYDFLG
NPEYCPDGHP INIDKNNLQR EEAFIPLDEM KEGSSGTVAR VTLPRETKER LTSLGIIAGE
DIEVRRKQKQ GCISVMAVGS EIALGRDIAK KIFITPK
//
