ID M1SXT4_9PROT Unreviewed; 496 AA.
AC M1SXT4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:AGG34326.1};
GN ORFNames=D521_1760 {ECO:0000313|EMBL:AGG34326.1};
OS beta proteobacterium CB.
OC Bacteria; Pseudomonadota; Betaproteobacteria.
OX NCBI_TaxID=543913 {ECO:0000313|EMBL:AGG34326.1, ECO:0000313|Proteomes:UP000011764};
RN [1] {ECO:0000313|EMBL:AGG34326.1, ECO:0000313|Proteomes:UP000011764}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CB {ECO:0000313|EMBL:AGG34326.1,
RC ECO:0000313|Proteomes:UP000011764};
RX PubMed=23599288;
RA Hao Z., Li L., Liu J., Ren Y., Wang L., Bartlam M., Egli T., Wang Y.;
RT "Genome Sequence of a Freshwater Low-Nucleic-Acid-Content Bacterium,
RT Betaproteobacterium Strain CB.";
RL Genome Announc. 1:e0013513-13(2013).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP004348; AGG34326.1; -; Genomic_DNA.
DR AlphaFoldDB; M1SXT4; -.
DR STRING; 543913.D521_1760; -.
DR KEGG; bprc:D521_1760; -.
DR PATRIC; fig|543913.3.peg.1738; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_1_0_4; -.
DR OrthoDB; 9803213at2; -.
DR Proteomes; UP000011764; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT DOMAIN 55..114
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 145..253
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 261..494
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 496 AA; 52912 MW; BCCA5C6F131BC693 CRC64;
MRAPEALFPS DWTKPKKQAD LLKLAKSILL EPTGLSEQDL HHTFGNMFTH QLDDADLYFQ
HTRSESWSLE EGIVKSGSFS IDQGVGVRAI YGDKTAFAYS DEINLEALNK AAKSTRVIGP
QGGTRAVASK IFTPVSNGLY SDLNPLDSLA PQEKIALLEG IERRAKARDP RIIQVMASLA
GEFDVVLVVR ADGLLAADVR PLVRVSVHVI AEQNGRRESG SSGGGARHDY HYFNTELINQ
YVDEAVDGAL INLDSRPAPA GPMTVVMGPG WPGVLLHEAV GHGLEGDFNR KGSSAFAGCI
GQRVAAKGVT VVDDGTLSGR RGSLNIDDEG TPTQCTTLIE DGILKGYIQD SLNARLMNMP
LTGNGRRESF ASLPMPRMTN TYMLAGKDDP QEIVASIKRG LYAVNFGGGQ VDITSGKFVF
SASEAYWVEN GKIQYPVKGA TIIGSGPESL KQVSMIGNDL KLDGGIGVCG KEGQSVPVGV
GQPTLRIDSL TVGGTA
//
