ID M1V6I2_CYAM1 Unreviewed; 928 AA.
AC M1V6I2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Similar to trefoil factor {ECO:0000313|EMBL:BAM78954.1};
GN ORFNames=CYME_CMB162C {ECO:0000313|EMBL:BAM78954.1};
OS Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC Cyanidioschyzon.
OX NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM78954.1, ECO:0000313|Proteomes:UP000007014};
RN [1] {ECO:0000313|EMBL:BAM78954.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM78954.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=15071595; DOI=10.1038/nature02398;
RA Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K., Yoshida Y.,
RA Nishimura Y., Nakao S., Kobayashi T., Momoyama Y., Higashiyama T.,
RA Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H., Ohta F., Nishizaka S.,
RA Haga S., Miura S., Morishita T., Kabeya Y., Terasawa K., Suzuki Y.,
RA Ishii Y., Asakawa S., Takano H., Ohta N., Kuroiwa H., Tanaka K.,
RA Shimizu N., Sugano S., Sato N., Nozaki H., Ogasawara N., Kohara Y.,
RA Kuroiwa T.;
RT "Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon
RT merolae 10D.";
RL Nature 428:653-657(2004).
RN [2] {ECO:0000313|EMBL:BAM78954.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM78954.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M., Maruyama S.,
RA Nishida K., Yagisawa F., Yoshida Y., Fujiwara T., Takio S., Tamura K.,
RA Chung S.J., Nakamura S., Kuroiwa H., Tanaka K., Sato N., Kuroiwa T.;
RT "A 100%-complete sequence reveals unusually simple genomic features in the
RT hot-spring red alga Cyanidioschyzon merolae.";
RL BMC Biol. 5:28-28(2007).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00779}.
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DR EMBL; AP006484; BAM78954.1; -; Genomic_DNA.
DR RefSeq; XP_005535240.1; XM_005535183.1.
DR AlphaFoldDB; M1V6I2; -.
DR STRING; 280699.M1V6I2; -.
DR EnsemblPlants; CMB162CT; CMB162CT; CMB162C.
DR GeneID; 16992363; -.
DR Gramene; CMB162CT; CMB162CT; CMB162C.
DR KEGG; cme:CYME_CMB162C; -.
DR HOGENOM; CLU_317465_0_0_1; -.
DR OrthoDB; 5474681at2759; -.
DR Proteomes; UP000007014; Chromosome 2.
DR CDD; cd00111; Trefoil; 2.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR Gene3D; 4.10.110.10; Spasmolytic Protein, domain 1; 2.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR017994; P_trefoil_chordata.
DR InterPro; IPR000519; P_trefoil_dom.
DR InterPro; IPR044913; P_trefoil_dom_sf.
DR PANTHER; PTHR13826; INTESTINAL TREFOIL FACTOR-RELATED; 1.
DR PANTHER; PTHR13826:SF14; P-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF00088; Trefoil; 2.
DR SMART; SM00018; PD; 2.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF57492; Trefoil; 2.
DR PROSITE; PS51448; P_TREFOIL_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00779}; Reference proteome {ECO:0000313|Proteomes:UP000007014};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..928
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004017875"
FT DOMAIN 564..611
FT /note="P-type"
FT /evidence="ECO:0000259|PROSITE:PS51448"
FT DOMAIN 629..686
FT /note="P-type"
FT /evidence="ECO:0000259|PROSITE:PS51448"
FT REGION 477..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 631..657
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00779"
FT DISULFID 641..656
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00779"
SQ SEQUENCE 928 AA; 99106 MW; 82584433CE998672 CRC64;
MFRARSLVRA LGVAVCLLLA ATFSVSVVAA LSPVSTVSWT WIGGETGIDN PGNYGTLNQT
SADSVPGGRY YSAAWVGSPS LVYLFCGVGY GNPFPSYFND LWTFNLTSHE WTWIGGSLDI
NNVGVYGTVG TGSPNSIPGG RYGSAYWQTD EQHFWLFGGY GFDVNGNVGD LNDMWRYDTE
TGIWTWFSGN DTINADPVYG PKDIYSQIYN PGGRDSAAFW LGADGLFWLF GGERNNGLDY
LSDLWSFNPV TFEWAYRGGS QLANQPGNYS APGVASNSNA PGARGFSHTW TDFEGNLWLF
GGYGYGNSTA LGQGDLNDLW VYNISQSVWI FIAGNTTIYV PGSYGSLGDF SPTSYPGARD
SGVSFVDSFG NLQLFGGEIF NTTNGNYVLL NDLWVFNIKI GQWAWINGSS AVDSLAVYGV
LNETGSSVVP GGREGPALWN TSGTDPVMFG GFGYSNTSGP GYLNDVFALS ETFFTPTSTP
TPTSTPTPTS TATSSVTASS TATSTITATV TSTFTLTPTP TSTPVCTNEI CGSPGQYTNQ
DACEQVGCCF NPETNACTLK SVSAACSAVP VTQRVPCGWS YIYPDECTAI PGCCWQPTAN
GILAPWCYYD IDHAPQASVA LQEVQAPVPV CPSPGAHRQP CGNAGINQFT CYAQGCCYDS
QAQNQWVQNG KQQSDFASNP YCFQPEKTCA VGEFERQPCT NAVNQNQQLN NNINNNQFVR
LLNTLLYGEQ HGTQRTSYSP QQCLEAGCCL GLGNECFQPM TEYVCQTYGY VSNSLSGTTG
NASNSSYIAC GPECCNAETQ NCTYNPFSNN NNQQQQQQLQ QQQQQQVLLP SFCVCKDPTK
QCGTYLIPSD NLVNKVRCCR ADEECINNQC VVISPTPTPS PVAVTATPSA TVSAAVSATV
STTASAAVSA TMSARASASV SGSASVSA
//
