ID M1VDN6_CYAM1 Unreviewed; 565 AA.
AC M1VDN6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=NADH dehydrogenase I iron-sulfur protein 75kDa subunit {ECO:0000313|EMBL:BAM80927.1};
GN ORFNames=CYME_CMM034C {ECO:0000313|EMBL:BAM80927.1};
OS Cyanidioschyzon merolae (strain NIES-3377 / 10D) (Unicellular red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC Cyanidioschyzon.
OX NCBI_TaxID=280699 {ECO:0000313|EMBL:BAM80927.1, ECO:0000313|Proteomes:UP000007014};
RN [1] {ECO:0000313|EMBL:BAM80927.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM80927.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=15071595; DOI=10.1038/nature02398;
RA Matsuzaki M., Misumi O., Shin-i T., Maruyama S., Takahara M.,
RA Miyagishima S., Mori T., Nishida K., Yagisawa F., Nishida K., Yoshida Y.,
RA Nishimura Y., Nakao S., Kobayashi T., Momoyama Y., Higashiyama T.,
RA Minoda A., Sano M., Nomoto H., Oishi K., Hayashi H., Ohta F., Nishizaka S.,
RA Haga S., Miura S., Morishita T., Kabeya Y., Terasawa K., Suzuki Y.,
RA Ishii Y., Asakawa S., Takano H., Ohta N., Kuroiwa H., Tanaka K.,
RA Shimizu N., Sugano S., Sato N., Nozaki H., Ogasawara N., Kohara Y.,
RA Kuroiwa T.;
RT "Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon
RT merolae 10D.";
RL Nature 428:653-657(2004).
RN [2] {ECO:0000313|EMBL:BAM80927.1, ECO:0000313|Proteomes:UP000007014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=10D {ECO:0000313|EMBL:BAM80927.1,
RC ECO:0000313|Proteomes:UP000007014};
RX PubMed=17623057; DOI=10.1186/1741-7007-5-28;
RA Nozaki H., Takano H., Misumi O., Terasawa K., Matsuzaki M., Maruyama S.,
RA Nishida K., Yagisawa F., Yoshida Y., Fujiwara T., Takio S., Tamura K.,
RA Chung S.J., Nakamura S., Kuroiwa H., Tanaka K., Sato N., Kuroiwa T.;
RT "A 100%-complete sequence reveals unusually simple genomic features in the
RT hot-spring red alga Cyanidioschyzon merolae.";
RL BMC Biol. 5:28-28(2007).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 75 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00005404}.
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DR EMBL; AP006495; BAM80927.1; -; Genomic_DNA.
DR RefSeq; XP_005536963.1; XM_005536906.1.
DR AlphaFoldDB; M1VDN6; -.
DR STRING; 280699.M1VDN6; -.
DR EnsemblPlants; CMM034CT; CMM034CT; CMM034C.
DR GeneID; 16995044; -.
DR Gramene; CMM034CT; CMM034CT; CMM034C.
DR KEGG; cme:CYME_CMM034C; -.
DR eggNOG; KOG2282; Eukaryota.
DR HOGENOM; CLU_000422_11_2_1; -.
DR OMA; QDQAMAY; -.
DR OrthoDB; 19999at2759; -.
DR Proteomes; UP000007014; Chromosome 13.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR Gene3D; 3.40.50.740; -; 1.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR015405; NDUFS1-like_C.
DR PANTHER; PTHR43105:SF13; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF09326; NADH_dhqG_C; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000007014};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 48..104
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 565 AA; 62235 MW; 09D5B01730DDC2FC CRC64;
MPALARTVLR TALSKVLHLH RERPLQHCRR FGALTSKPYA FRARPWELKS TESIDVFDGV
GSNIRIDAVG TEVRRILPRL NEEVNEEWIS DKTRFAYDGL KRQRLTVPMV RIHTGEANEQ
LVGVDWYKAR AILVNKLVSA IREAATPATT QRSAFEAHAI IGPYADCESI AALRRIFYSM
FPEGTAFVHV QGHANTGTPP TDFRYAYCAN TTLAGLEHAD VILLVATNPR VEAPLLNNRI
RKAVLFGNAR VGLIGCHADL TYNREHLWHL GTSPATLLRI AQGRHAFCSV LAKAQRPAII
VSQQAFQRHD GAAIFGCLAT LVDHVPRLVP RDGSWNGLNV LHTAANTVGA LDLGFDHTLK
GNRWIDQSGA QQTSEQPWAR AKLLYLLGAD DIDGLEELPE TCYVVYQGHH GDYGASIADL
ILPGAAYTEK NGTFVNTEGR VQRTARAFLP PGQAKVDAEI LDELLVGLDH AAGFFDAAQE
MEFLAPHLGV QYGLQEPDLI RTPNTGQVQL GGAKAERARS LPLSPMPFGP VIENFYMTDP
ITRASATMAK CVRVARYSNF EESSS
//
