ID M1VJJ0_STRSU Unreviewed; 459 AA.
AC M1VJJ0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Cps2E {ECO:0000313|EMBL:CYW13480.1};
DE SubName: Full=Initial sugar transferase {ECO:0000313|EMBL:BAM94549.1};
GN Name=cps6E {ECO:0000313|EMBL:BAM94549.1};
GN Synonyms=wcaJ {ECO:0000313|EMBL:CYW13480.1};
GN ORFNames=ERS132453_01572 {ECO:0000313|EMBL:CYW13480.1};
OS Streptococcus suis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1307 {ECO:0000313|EMBL:BAM94549.1};
RN [1] {ECO:0000313|EMBL:BAM94549.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=2524 {ECO:0000313|EMBL:BAM94549.1};
RX PubMed=23416996; DOI=10.1128/AEM.03742-12;
RA Okura M., Takamatsu D., Maruyama F., Nozawa T., Nakagawa I., Osaki M.,
RA Sekizaki T., Gottschalk M., Kumagai Y., Hamada S.;
RT "Genetic analysis of capsular polysaccharide synthesis gene clusters from
RT all serotypes of Streptococcus suis: potential mechanisms for generation of
RT capsular variation.";
RL Appl. Environ. Microbiol. 79:2796-2806(2013).
RN [2] {ECO:0000313|EMBL:CYW13480.1, ECO:0000313|Proteomes:UP000074436}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSS91 {ECO:0000313|EMBL:CYW13480.1,
RC ECO:0000313|Proteomes:UP000074436};
RG Pathogen Informatics;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the bacterial sugar transferase family.
CC {ECO:0000256|ARBA:ARBA00006464}.
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DR EMBL; AB737818; BAM94549.1; -; Genomic_DNA.
DR EMBL; FIIO01000021; CYW13480.1; -; Genomic_DNA.
DR RefSeq; WP_024386404.1; NZ_RSDP01000018.1.
DR AlphaFoldDB; M1VJJ0; -.
DR Proteomes; UP000074436; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR003362; Bact_transf.
DR InterPro; IPR017475; EPS_sugar_tfrase.
DR NCBIfam; TIGR03025; EPS_sugtrans; 1.
DR PANTHER; PTHR30576; COLANIC BIOSYNTHESIS UDP-GLUCOSE LIPID CARRIER TRANSFERASE; 1.
DR PANTHER; PTHR30576:SF10; SLL5057 PROTEIN; 1.
DR Pfam; PF02397; Bac_transf; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:BAM94549.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..453
FT /note="Bacterial sugar transferase"
FT /evidence="ECO:0000259|Pfam:PF02397"
SQ SEQUENCE 459 AA; 53095 MW; B000F906C09EAA8C CRC64;
MFIDVKHRRI RLLLIDLISV IISASITSQI PNADLSRSGI LIILMIHFFA FYISNLYADF
ENRGFLKEFE KIFLYSLVFA ILLTAVSFFL ENNFEFSRRG LIYFTLMNSV FVYITNCTIR
SYKDYIFLNS DYQHKIILLT TLERWQGMRK LLESKKLLQK NIVALVILDI QDKEFGLSIP
VFNSVEDAVG FATRGVVDQI FINLPSEYYD LKQLVSEFEI LGIDVSVDIN SFGFKELKNK
KIELLGNHSI VTFSTNFYDP SHIFMKRLLD IIGAIIGLVF CGLVAIILVP LIRKDGGPAI
FIQKRIGKNG RIFKFYKFRS MCIDAERRKK ELTEQNQMKG GMFKVDNDPR ITPIGHFIRK
TSLDELPQFY NVLIGDMSLV GTRPPTMDEF ENYTPSQKRR LSFKPGITGL WQVSGRSNIT
DFDEIVKLDV EYIDNWNIWS DIKILLKTIK VVFLKEGSK
//
