ID M1VZ65_CLAP2 Unreviewed; 1756 AA.
AC M1VZ65;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Related to antiviral protein and putative helicase {ECO:0000313|EMBL:CCE34662.1};
GN ORFNames=CPUR_08597 {ECO:0000313|EMBL:CCE34662.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE34662.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE34662.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE34662.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE34662.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAGA01000101; CCE34662.1; -; Genomic_DNA.
DR STRING; 1111077.M1VZ65; -.
DR VEuPathDB; FungiDB:CPUR_08597; -.
DR eggNOG; KOG0949; Eukaryota.
DR HOGENOM; CLU_002305_2_0_1; -.
DR OrthoDB; 33910at2759; -.
DR PhylomeDB; M1VZ65; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18025; DEXHc_DDX60; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR44533; DEAD/H RNA HELICASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR44533:SF4; HELICASE ATP-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:CCE34662.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801}.
FT DOMAIN 730..903
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1174..1347
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 491..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1151..1181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1661..1728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..530
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1051..1066
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1676..1692
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1756 AA; 197916 MW; D6044626752D9DDF CRC64;
MAFNRQDEDM QLRCLSLIKV DIVGDFAGKE LFAIHGDSLL LHCIRKAKVD IEIGFQLLHA
VFAVEAFIET LNKRGCNFNI VWFSDHEKLC MPEDVSPTAK WNYCLTRAII VKHLERRNSD
CAAGSTSSLS MHSSSFQRYL DENAIYFFLS LGGQDDEDLS HNGVQYMQLL RWLSSKGYSI
AALDSLEISS SKVYARVRSP AMMKEAIELP EVQQIPRSKS VNELKSSCDM LLFDSSPWGD
GLPCSERDRV SLVGLTNTLL LDDRQRMKHC ALAYIIHLSL LRHLDLSQRS CTEITLPTLE
QKSMDEFLSS FNNICTSFVE NMIPSRNWDL FDLVDGRILR QIYVNLANIS LPKLIIDEVL
RYANVLRQST QVDLSRSIPQ YDMVRTSNPA VALIDNSTSC SVLDFTHPVL DAFLSEMSLS
TQRSITSQST LKIFQELSHW HNARISIDKK QIPKQKTLLA MKRHQRLMNN ILSYSASLTN
ASGKTINPET IVSEVQMKPP SKKSNKVNRG VDGKAPKLPT SHEPKHKKPA ASGGRQAAMK
EANLIQARKS NELLKKALSY WDRLCGQFEH ETDLDSRYRK TVKYLAELVD QDMGVIRAEA
SLYLCNCLAL IIHNARKKSK KIDEMGLMAI IWSKLLDINS LSLSNEGADL FKLFAAAVKF
PASVAPDASL KGRKLPFRHI MAYLGNKLSI PLSSLHFQLL HCGPYLERGF DSAPDPRVLF
NPDAWQRKVL DAIDANQSLF VVAPTSAGKT FLSFYAMKKV LQSNDDDVLV YVAPTKALVN
QIAAEVQARF SKSYKNAGSS VWAIHTRDYR INSPKGCQIL ITVPHILQIL LLHPSNSSES
KAWSLRIKRI IFDEVHCIGQ ADDGVIWEQL LLIAPCPIIA LSATVGNPED FRAWLETSEK
AKGHELTMIA HSSRYSDLRK FVYHLPIEQN FQGLKSAEGI HIPGLDEGQH AALSFSHVHP
VATLVNRNRG KLNDINLEPR DCFVLWKYMS KHQTKDFCIS DNLNPEHSFS GIIKKSDVTK
WEAALKRVME GWIQAADSPF PSLRADLQSL TAQNAPVNSK TPRVKEPTSA KSVDPGTEAS
DLRNAALPLL TDLHRHESLP AILFNYDRTY CERVLCFVND QLKVAEDKWK ADSPAWQRKI
AKFEEWKRSG VKSKQKVNRT GPNQRRQDEG EHSKLDSMQD EADKDISRWE SFDPEAPLEM
FSFADRTKML DSEFEIQIER LKWQNLKPEI LGALRRGLGV HHAGMNREYR QIVEMLFRKG
YLRVVIATGT LALGINMPCK SIVFFGDSVF LTALNYNQCA GRAGRRGFDV LGNVVFVGLR
PERVFEIMSS RLPDLRGQFP LSTTLVLRLM GLLHHTNNSP YAVRIMKSLQ VQSRLFLGGP
SDQMSIKHHL RFSIEYLRRQ DLLSEHGAPL NFAGLVGHLY FTENAVFAFH SLLRGGYFHR
ICRNINRTKY GVSQQLMLIL SHLFGRIPLR MADAKAITDK EHRSPSIVVL PALPKAAEDI
LTEHNKETLH IFRNYVGSFV EQHLYDQPDN QLPLTNCAIL KKTGADTIEA SSFLDIVPPT
KLRSAFAALS GFTDEFESIH DLCTTVRAGV FLEESAVPYI PLYPNDDANM HWNAYLYDFF
KHGSLEALVR YNGIKAGDVW FHLKDFSLVL AAIVTTLQNS HGSAVQQQST GPPKPDDLEE
SWDSEMKPEI SSQDENTSRA QDNEGGGPAD ALTESEAEEE GKEAEKYDAE ESLANILLAF
MELQSQFNEA FYKVGA
//
