ID M1W1Q6_CLAP2 Unreviewed; 772 AA.
AC M1W1Q6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CPUR_00452 {ECO:0000313|EMBL:CCE26980.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE26980.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE26980.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE26980.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE26980.1}.
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DR EMBL; CAGA01000002; CCE26980.1; -; Genomic_DNA.
DR AlphaFoldDB; M1W1Q6; -.
DR STRING; 1111077.M1W1Q6; -.
DR VEuPathDB; FungiDB:CPUR_00452; -.
DR eggNOG; KOG0017; Eukaryota.
DR HOGENOM; CLU_000384_38_1_1; -.
DR OrthoDB; 2734036at2759; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006338; P:chromatin remodeling; IEA:UniProt.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00024; CD_CSD; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00665; rve; 1.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 369..528
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT DOMAIN 678..736
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 749..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..764
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 89360 MW; EA2D7FDFAA479501 CRC64;
MVDPAKIAVV RDWEVPTTVK AVQSFLGFCN FYRRFVLEYG RIARPLNALT KKGAPFVWTA
TEQEAFQELK NRLLSAPILA HFDGKRKTRV ETDSSDGVCA GVLVQEDPDT KQVHPVAFYT
KTMNSAECNY PIHDKELLAI ILALKEWRAE LRSVTGPFEV ITDHEALVHF SMKQLLSYRQ
ARWSEELSGW NMQLSYRPGK ENILADALSR KWEDLQTQKA MKAATRTKNL FIPVALFTGK
LCEDAGKEVE LLDELLQSNK SDAELEVYRQ LAKEKSGGWS LTEQGLLLKG DRLFVPERNN
LRTRVLEYIH LDKALCHPGR NKMRRLVSDR YFWPRHMGDV DVYVRNCLTC RRSQPTHDKT
PGLLHPLPIP DRPFQKVSVD FKSMSLDKHG FDNVMVVMCR LSKQSITIPC HKTVTAAQMA
RLWLDHIWRH FGPPEEVVSD RGPQFISAFW EEFCQLLGIK RKLSTSGHPQ TDGQTENFNQ
TLDIRLRPLV DHFQDDWSEF VAMVDYAQGA LPHESTGLSP FEVRNGFQAP LNMDWTQKTA
KFKSANEEMN RTTAVRYAER MHLAWTIARA GMEKAQERQC KQANKKRREP DFGVKDMVMV
SRKKWPTDRP SDKLDMPWAG PYQITEQVGH SYRVDMGPNF KMHNVFHADR LRKAPNDPLP
GQRIVPPEPE VIDGNLEYEV DKILSSRVFR GKLQYKVAWT GWDPDEEWYD AGNFKNAPHR
LYQYHEEHPD KPGPPKRLEQ WRLAWDKDEE LMDHDEDNAP VSTKGARTRR RR
//
