ID M1W2W6_CLAP2 Unreviewed; 1783 AA.
AC M1W2W6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Related to DNA repair protein rhp54 {ECO:0000313|EMBL:CCE27975.1};
GN ORFNames=CPUR_01449 {ECO:0000313|EMBL:CCE27975.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE27975.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE27975.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE27975.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE27975.1}.
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DR EMBL; CAGA01000006; CCE27975.1; -; Genomic_DNA.
DR STRING; 1111077.M1W2W6; -.
DR VEuPathDB; FungiDB:CPUR_01449; -.
DR eggNOG; KOG1015; Eukaryota.
DR HOGENOM; CLU_001161_0_0_1; -.
DR OrthoDB; 2787289at2759; -.
DR PhylomeDB; M1W2W6; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR044574; ARIP4-like.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45797:SF1; HELICASE ARIP4; 1.
DR PANTHER; PTHR45797; RAD54-LIKE; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801}.
FT DOMAIN 896..1082
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1254..1418
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 106..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1551..1570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1602..1653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 816..843
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 106..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1551..1565
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1629..1653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1783 AA; 199154 MW; 5B519A372C3B889B CRC64;
MEDTRHTDPF LWDEDAVILC LCSTSRPCSR DLREFASRIR ENEIDGHSLL TYDLVGEASG
HDLRNELYQT LNVRLLKHKN ALGEAVMKLR RRSRLFQQWK LDHFDGRESE ERQSHDHVRE
TSTPMRTTPQ SNAVMVLQKP LAVDEPAVVT PTFASTTPKP NPLTSHDNTG DPHGVRTKGV
VGGKPSKPDI SAQTSLPFAI ADGSTPSNQL KRKRVAPQQL QEQPVNLLPV PLPTEADNLH
HDEAKSLLGT QDSASLHDSE GKFAYLGKGV IHVRHVKSPR IPLTRQLHGE GKAIRTSVPT
TFPPGKRRVI DKLMRRLLVK NSRNMNALNG GAGLVESSGS LSESDKILEL DDLPDELDKE
TREEMEIEQA EVKKKLEASS SFLSSEKVQQ ILDEEVSGVE RDWNERKLPK YCRKANSLWK
DASRRGTKLE LFVRAVKEAK RCDDRIKTLR AEIMEQAWER DRHLRLQAKC LEQSVEDRLY
QSWLADILNS RFAPAKPPKL MAPLTKKTPL KRKLGQVLSD EEILTSSDDE SFIVDDGPVD
EAATHVELAQ FSPTVPIKRS QSPVMAPASP LYIDLTQIDS SVPNSPAGKP NINDSDVGAP
KRLRATLVDP ESKSIVTKRN KPEPEPEPPS QTKALSWPAK YPDVKRIANY RPSHWSKQKE
RYALVISLLW RLEHSRRSAV LELVRENGVE ESFNLTVARY ISSPIQDVSR LAEKSPDTLA
FDVSRLFLCF LKVKNLKESR LINLKSVSIQ RLKNQRGKDS WAVWHDFLTQ MAPLFPQDNQ
IWREDVSDVE GISGDAEGES TPAIMRRSAR KEIIQNKDAL DLREREERRA EELEARRLRL
RANLGSATIM SRDKSRLIIN ESKQDDQSFI YINQYLGDRI KDHQIEGVRF MWNQIIQDSA
LRQGCLLAHS MGLGKTMQVI TLLVAIQEAS RSSDPSTTSQ IPSDLQQSKT LVLCPAGLVN
NWIDELLLWD VDRILGGPYA IDSTMSAEER VATAEQWSQN GGVLVIGYTM LNSIYGKAPE
RTFFEKPNLV VADEAHTLKN PDTQAHAVCS RFRTMSRIAM TGSPLANNIE EYHSMIDWVA
PNYLGPISEF RCIYANPIQQ GLSAGSGGSE KRRALKMLQV LKQTVAPKVH RATIKSCMEE
DLPPKREFVL CVAPRPLQVS LYNLYLSAAR ERVTQGKYKQ AAIFDLVFRL RTICAHPCVF
AKNYCKPKEQ PALTNEQPAL TNEQPALAKS IVKATLDSFG PDWGIPSAST KVEMLIKILD
HARNEGDKVL VFTHSLPTLN YLNDLFISQG RAFEKLDGEY PIKKRQDLIK TFNSGQAEVA
LISTKAGGVG LNIHGANRVV IFDFGFNPVQ EQQAVGRAYR IGQTKPVTVY HFVTAGTFEH
DMHGNSVFKA QLASRVVDKK NPVSWGNKKL EIMKHDLIET QPKDLTSHIG QDSILDELIR
HSGSDGLIRE IVSTDTYEEE DEKAPLSLEE QIEADNMVRM HQLRHSNPEE FQRLKDLNDY
RSSQSTKPGP INVAHNVSAA SVAIPSPTSN ETVADGQLRR AAGFQILAES QMQPTGANGT
TPAAEPSSHP MYAPAVAPAV APAVAPAQDV IYVSASKASI QHSSPLMPIP GAQTYFGHDA
RDSSKPPAAS EPDDSQSTRP PVQAQTQDKQ NLFSTSIKCP LKDKFRDKVA AKLDGVLQQN
PTYSEATLAE VLNKITDSIH ATRQSLNLGF LPDSRHWSTL VDLAENDRFV AALISGVLEA
EPLARMSIDE LTKTMDELKE MPLTELKTQV RRGVVNGGRE FII
//
