ID M1W368_CLAP2 Unreviewed; 511 AA.
AC M1W368;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Probable endo-1,4-beta-xylanase {ECO:0000313|EMBL:CCE28250.1};
GN ORFNames=CPUR_01724 {ECO:0000313|EMBL:CCE28250.1};
OS Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX NCBI_TaxID=1111077 {ECO:0000313|EMBL:CCE28250.1, ECO:0000313|Proteomes:UP000016801};
RN [1] {ECO:0000313|EMBL:CCE28250.1, ECO:0000313|Proteomes:UP000016801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=20.1 {ECO:0000313|EMBL:CCE28250.1,
RC ECO:0000313|Proteomes:UP000016801};
RX PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA Yoshida R., Zeng Z.;
RT "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT Clavicipitaceae reveals dynamics of alkaloid loci.";
RL PLoS Genet. 9:E1003323-E1003323(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCE28250.1}.
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DR EMBL; CAGA01000007; CCE28250.1; -; Genomic_DNA.
DR AlphaFoldDB; M1W368; -.
DR STRING; 1111077.M1W368; -.
DR VEuPathDB; FungiDB:CPUR_01724; -.
DR eggNOG; ENOG502SI39; Eukaryota.
DR HOGENOM; CLU_009397_6_0_1; -.
DR OrthoDB; 5470935at2759; -.
DR PhylomeDB; M1W368; -.
DR Proteomes; UP000016801; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0045493; P:xylan catabolic process; IEA:UniProtKB-KW.
DR CDD; cd08990; GH43_AXH_like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43772:SF2; BETA-1,4-XYLOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Polysaccharide degradation {ECO:0000313|EMBL:CCE28250.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016801};
KW Signal {ECO:0000256|SAM:SignalP};
KW Xylan degradation {ECO:0000313|EMBL:CCE28250.1}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..511
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004019317"
FT REGION 324..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 180
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 511 AA; 56112 MW; BA14E8F37A9D4697 CRC64;
MAVTRLSFGR LFNIFLLLSV ADCQIPFVSD GNPILSNGTY YTADPGPIVV NGSLYIIAGH
DSAPKDDNNF IINHWHLLAS DDPNPAGGNW KMYPDFVAPH TVFRWADTAA AYASQIVLGP
DGGYYLYSPV SQSKTSSSDP FGIGVARADK IEGPYVDHHP RGPIVSQSYP APGNDIENID
PTVLVDNDRV FMYWGTFGEL RGVELDKKDM STFVGDIVTV TSLNGFFEAA WLMKRGETYY
MIYAANNVGK ECTPTLYHAC LAYGTSSGPL GPWTYRGVIL GIVSSTTSHS GAVAIKDQWY
LVYHTADAHS GGNFRRSVAF DKMDFDDSTS PPRIRPVQQT HRPEPAPKPT YQRQQLAVAS
SSPPCIDRYW IEAVHDQKIP NNPLPPEYWS TYSDEGTIPV QSTVTYSWET EQELNGVGMS
FFADSPAGSV EGVAPPTEWF VEYKSSNGSW TAVRNSTGYS TQVTTHPKTT NFDVIKTKGL
RATLRAPTNG TWTAGVGIKE WLVYSTTKAV V
//
