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Database: UniProt
Entry: M1YWQ8_NITG3
LinkDB: M1YWQ8_NITG3
Original site: M1YWQ8_NITG3 
ID   M1YWQ8_NITG3            Unreviewed;       466 AA.
AC   M1YWQ8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   05-JUL-2017, entry version 33.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:CCQ89934.1};
GN   ORFNames=NITGR_190044 {ECO:0000313|EMBL:CCQ89934.1};
OS   Nitrospina gracilis (strain 3/211).
OC   Bacteria; Nitrospinae/Tectomicrobia group; Nitrospinae; Nitrospinia;
OC   Nitrospinales; Nitrospinaceae; Nitrospina.
OX   NCBI_TaxID=1266370 {ECO:0000313|EMBL:CCQ89934.1, ECO:0000313|Proteomes:UP000011704};
RN   [1] {ECO:0000313|EMBL:CCQ89934.1, ECO:0000313|Proteomes:UP000011704}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3/211 {ECO:0000313|EMBL:CCQ89934.1,
RC   ECO:0000313|Proteomes:UP000011704};
RX   PubMed=23439773; DOI=10.3389/fmicb.2013.00027;
RA   Luecker S., Nowka B., Rattei T., Spieck E., and Daims H.;
RT   "The genome of Nitrospina gracilis illuminates the metabolism and
RT   evolution of the major marine nitrite oxidizer.";
RL   Front. Microbiol. 4:27-27(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCQ89934.1}.
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DR   EMBL; CAQJ01000021; CCQ89934.1; -; Genomic_DNA.
DR   RefSeq; WP_005006869.1; NZ_HG422173.1.
DR   EnsemblBacteria; CCQ89934; CCQ89934; NITGR_190044.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000011704; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011704};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011704}.
FT   DOMAIN      163    295       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      374    443       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     171    178       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   466 AA;  53560 MW;  994C3BA98473AA9B CRC64;
     MDALWKNCLD HIEQKILPEN FNTWFTPLYP CAKNENTLTL VVPNRFFERC LRENYLELIQ
     ETLEYFANKK LEVCFQVNGI SSGIETPFNG NGNGNGNGHP PVSAPSEARM ETPASSPHVE
     VGESSRTESF LNPKYTFDRF VIGPNNQFAH AACQAVAQKP AYTYNPLFLY GAVGLGKTHL
     LHAIGNQISN QNPNLRVRYI SAERFTVDLI ESIKRDKMAA FRERYRPLDV LLVDDIQFIA
     GKERTQEEFF YTFNSLYEYH KQIVVSSDRY PKDMKNIEER LRSRFESGLI ADIMPPDLET
     KMAILYKKAD FHEKEISQDV AMFLANNIKS NIRELEGILL RVIAYSSFTR RDIDLELAKE
     VLKDFTVDKN KNFSIANIQK TVAQYFSIRV SDLKSKKRSR DISIPRQIAM YICREYTQAS
     LPEIGRQFGG KDHTTVIFSH RKISSLVKEN NEMTGSIQQI LNILES
//
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