ID M1Z2L2_9FIRM Unreviewed; 295 AA.
AC M1Z2L2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Diacylglycerol kinase catalytic region {ECO:0000313|EMBL:SHD78495.1};
GN ORFNames=CUESP1_3169 {ECO:0000313|EMBL:SHD78495.1};
OS [Clostridium] ultunense Esp.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Tepidimicrobiaceae;
OC Schnuerera.
OX NCBI_TaxID=1288971 {ECO:0000313|EMBL:SHD78495.1, ECO:0000313|Proteomes:UP000245423};
RN [1] {ECO:0000313|EMBL:SHD78495.1, ECO:0000313|Proteomes:UP000245423}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Clostridium ultunense strain Esp {ECO:0000313|EMBL:SHD78495.1};
RA Manzoor S.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the diacylglycerol/lipid kinase family.
CC {ECO:0000256|ARBA:ARBA00005983}.
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DR EMBL; LT669839; SHD78495.1; -; Genomic_DNA.
DR RefSeq; WP_005587368.1; NZ_LT669839.1.
DR AlphaFoldDB; M1Z2L2; -.
DR HOGENOM; CLU_045532_1_0_9; -.
DR OrthoDB; 142078at2; -.
DR Proteomes; UP000245423; Chromosome chri.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR005218; Diacylglycerol/lipid_kinase.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR045540; YegS/DAGK_C.
DR NCBIfam; TIGR00147; YegS/Rv2252/BmrU family lipid kinase; 1.
DR PANTHER; PTHR12358:SF106; LIPID KINASE YEGS; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF19279; YegS_C; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SHD78495.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245423};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..131
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 295 AA; 33044 MW; DBFE9658985C26D5 CRC64;
MEKVKVICNP SSGRQTIQRR VDYLCNLLIN DGYVVGKFNT MKKDDAMHEA MKACNEDWDF
IIACGGDGTV NEVAKGIARC ERKIPVAILS AGTVNDFANH MELPRNIDDF FQMIKNKKIK
TVDLGKVNDE YFINVAAGGL LTNVGYQVPP EAKAIFGRMA YYMEGLKEIP KQKFKPIRVK
FESEEYIKEE DILLFLISNS ASIGGFKRLA PDANVSDGYL DVVIIKKSEV QDLAQIFINI
FRGEHVNHPN VSYFKSKKIL VDTAEDVVID IDGEYGGKLP AVFEAEPNGF KIFVP
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