ID M1Z8X1_NITG3 Unreviewed; 547 AA.
AC M1Z8X1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Putative Methyltransferase, Cysteine dioxygenase type I family {ECO:0000313|EMBL:CCQ89543.1};
GN ORFNames=NITGR_130009 {ECO:0000313|EMBL:CCQ89543.1};
OS Nitrospina gracilis (strain 3/211).
OC Bacteria; Nitrospinae/Tectomicrobia group; Nitrospinota; Nitrospinia;
OC Nitrospinales; Nitrospinaceae; Nitrospina.
OX NCBI_TaxID=1266370 {ECO:0000313|EMBL:CCQ89543.1, ECO:0000313|Proteomes:UP000011704};
RN [1] {ECO:0000313|EMBL:CCQ89543.1, ECO:0000313|Proteomes:UP000011704}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3/211 {ECO:0000313|EMBL:CCQ89543.1,
RC ECO:0000313|Proteomes:UP000011704};
RX PubMed=23439773; DOI=10.3389/fmicb.2013.00027;
RA Luecker S., Nowka B., Rattei T., Spieck E., and Daims H.;
RT "The genome of Nitrospina gracilis illuminates the metabolism and evolution
RT of the major marine nitrite oxidizer.";
RL Front. Microbiol. 4:27-27(2013).
CC -!- SIMILARITY: Belongs to the cysteine dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00006622}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCQ89543.1}.
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DR EMBL; CAQJ01000015; CCQ89543.1; -; Genomic_DNA.
DR AlphaFoldDB; M1Z8X1; -.
DR STRING; 1266370.NITGR_130009; -.
DR HOGENOM; CLU_497664_0_0_0; -.
DR InParanoid; M1Z8X1; -.
DR OrthoDB; 7059163at2; -.
DR Proteomes; UP000011704; Unassembled WGS sequence.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd10548; cupin_CDO; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010300; CDO_1.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF05995; CDO_I; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000313|EMBL:CCQ89543.1};
KW Iron {ECO:0000256|PIRSR:PIRSR610300-51};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR610300-51};
KW Methyltransferase {ECO:0000313|EMBL:CCQ89543.1};
KW Oxidoreductase {ECO:0000313|EMBL:CCQ89543.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011704};
KW Transferase {ECO:0000313|EMBL:CCQ89543.1}.
FT DOMAIN 340..430
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
FT BINDING 85
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR610300-51"
FT BINDING 87
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR610300-51"
FT BINDING 135
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR610300-51"
SQ SEQUENCE 547 AA; 62480 MW; 2FE0E610E97A8F6C CRC64;
MDAKSPPFPE SLKALIGAVE KETHWSPQRA AQILREADIT QQELMPWAFF DHPAKDSYGR
KLVHDGGHYE MMVMSWNPGD VSALHDHGYA QWGAVKVFGP AEHASFWLIN GELHTQSRTR
LKPGDVLHVG HEWVHQMGNT SGIQFLTFHL YGCVGRRGGI TANARVFDLD ANQVHLTNNG
VFFALPESAI SARIAGPMPD FMTHFRHQVE LKHRLDRMRA ASDTQSLPPL LDTRDQRVTD
DLFDARHWDA FEHDLFLHVD TGTGCMTDLG YWQRLRQEVQ TVAELQEKLR EEADNGDPFD
TYAELYDAVV GEPCLDSFME SYLEFAFRKY RLLNKGGRFL SLGCGTGMVE NHLVRRGRVP
KDRMHGIDKS PAMVKVAKER INAWEGDLLE IDEENAWDVT YNGLNVFQYL RPKEMEQAIR
VAARITRPGG YFVGDFITPD HIRVYPHVIR SNCGNVISLR QPELIEQEGH IFQRSAILNV
SRLHGTLQIT DEGRHLRCLP SVTRVRRWFE EAFQGQVEVY DAATLHPLDP SDETCWSTRY
LVIAKKK
//
