ID M2PTR8_9PSEU Unreviewed; 995 AA.
AC M2PTR8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Putative transcriptional regulator {ECO:0000313|EMBL:EMD27963.1};
GN ORFNames=C791_1860 {ECO:0000313|EMBL:EMD27963.1};
OS Amycolatopsis azurea DSM 43854.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis.
OX NCBI_TaxID=1238180 {ECO:0000313|EMBL:EMD27963.1, ECO:0000313|Proteomes:UP000014137};
RN [1] {ECO:0000313|EMBL:EMD27963.1, ECO:0000313|Proteomes:UP000014137}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43854 {ECO:0000313|EMBL:EMD27963.1,
RC ECO:0000313|Proteomes:UP000014137};
RA Khatri I., Kaur I., Subramanian S., Mayilraj S.;
RT "Genome assembly of Amycolatopsis azurea DSM 43854.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMD27963.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ANMG01000020; EMD27963.1; -; Genomic_DNA.
DR RefSeq; WP_005154885.1; NZ_MUXN01000022.1.
DR AlphaFoldDB; M2PTR8; -.
DR PATRIC; fig|1238180.3.peg.2459; -.
DR OrthoDB; 7628974at2; -.
DR Proteomes; UP000014137; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF13176; TPR_7; 2.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 6.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 1..92
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 786..819
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 1..92
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 995 AA; 107945 MW; FDBC93FDC6DAB9E0 CRC64;
MEFRVLGAVE AWAGGDPVDL GSPKQRLVLA VLLLEAGKPV PRDRIIDLLW PEEPPASARN
TVQALVSRLR AVFRGAGGPE IVSEGTRYLL RVDPRRVDVH RFTELTSQAR EADDETAVEL
LDEALGLWRG EALSDVVSGE VAQRLRGGMN EERWTALEDR ADAQLRLGRG RQVLAELTEL
VAAHPLRQRF VGQLMLALHR EGRTDDALEA FRALRDRLGT ELGLDPSPEL RRLEAAILAA
DPALEPLAAV TKPEPIRPAQ LPHDVRGFAG RASELERLDE ATRHAGEGTD IWVISGTAGV
GKTALAVRWA HRVRDAFPDG QLYLDLRGFD PDHEPLTPAV ALTQLLQALG TAPKAIPPDT
DTRAALLRSL LADRRVLLVL DNVRDTGQVL PLLPPSGTVL VTSRQRLGDL IARTGARALP
LSVLPAEDAR HLLEAVLGSE TVAAEAVAAA ELARLCGHLP LALRIAAANL GASGEPEIAE
LARELAGGDP LAELTVDGAE ESAVTTAFGV SYRALPEEHR LLFRRLALVP GQTFTAPAAQ
ALTGAPHSKA NQQLKALAAA HLVERYTPGR YRFHDLLRSF AAGRTLSEDA KSERDTAERR
LFESYLTTAD AAGRVLIPHF LRLPREEPED KPFGDTEEAL AWLDAEWPNL AAAVEHSAEH
GPPEFSWHLA DALRAFFHQR GHHAEWIDTA STALKAARRS GAGQAQAAMH LSIALACVNS
GRYDEAREHL TSALRGDLLD GWDAGRAAVL NNLSAVHQRL GAPQEAIRCG LESLRLCEEL
NLPGISMALA NLGFPYWQTG QLDEALANFT RALTVAERDG ARFSVAVLLV DLGNVHRDLG
LPDGAYDFYT RALAANRELG YTYGEATALS GRAVLESKRD PSEQNRADAL EAVELTRKIG
DRGTEAWTLV GLGEVCLRLG LPEEAAEHHR LALSIARTTS FFWCEAAART GLAETLLTLG
KRAEARTHGE LALELAARSG YRLVEERAKL ILDEL
//
