ID M2QS16_CERS8 Unreviewed; 1336 AA.
AC M2QS16;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 13-SEP-2023, entry version 43.
DE RecName: Full=REM-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CERSUDRAFT_112137 {ECO:0000313|EMBL:EMD39883.1};
OS Ceriporiopsis subvermispora (strain B) (White-rot fungus) (Gelatoporia
OS subvermispora).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Gelatoporiaceae; Gelatoporia.
OX NCBI_TaxID=914234 {ECO:0000313|EMBL:EMD39883.1, ECO:0000313|Proteomes:UP000016930};
RN [1] {ECO:0000313|EMBL:EMD39883.1, ECO:0000313|Proteomes:UP000016930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B {ECO:0000313|EMBL:EMD39883.1,
RC ECO:0000313|Proteomes:UP000016930};
RX PubMed=22434909; DOI=10.1073/pnas.1119912109;
RA Fernandez-Fueyo E., Ruiz-Duenas F.J., Ferreira P., Floudas D.,
RA Hibbett D.S., Canessa P., Larrondo L.F., James T.Y., Seelenfreund D.,
RA Lobos S., Polanco R., Tello M., Honda Y., Watanabe T., Watanabe T.,
RA Ryu J.S., Kubicek C.P., Schmoll M., Gaskell J., Hammel K.E., St John F.J.,
RA Vanden Wymelenberg A., Sabat G., Splinter BonDurant S., Syed K.,
RA Yadav J.S., Doddapaneni H., Subramanian V., Lavin J.L., Oguiza J.A.,
RA Perez G., Pisabarro A.G., Ramirez L., Santoyo F., Master E., Coutinho P.M.,
RA Henrissat B., Lombard V., Magnuson J.K., Kuees U., Hori C., Igarashi K.,
RA Samejima M., Held B.W., Barry K.W., LaButti K.M., Lapidus A.,
RA Lindquist E.A., Lucas S.M., Riley R., Salamov A.A., Hoffmeister D.,
RA Schwenk D., Hadar Y., Yarden O., de Vries R.P., Wiebenga A., Stenlid J.,
RA Eastwood D., Grigoriev I.V., Berka R.M., Blanchette R.A., Kersten P.,
RA Martinez A.T., Vicuna R., Cullen D.;
RT "Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete
RT chrysosporium provide insight into selective ligninolysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:5458-5463(2012).
CC -!- SIMILARITY: Belongs to the RICTOR family.
CC {ECO:0000256|ARBA:ARBA00008878}.
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DR EMBL; KB445793; EMD39883.1; -; Genomic_DNA.
DR STRING; 914234.M2QS16; -.
DR HOGENOM; CLU_001013_0_1_1; -.
DR OrthoDB; 90320at2759; -.
DR Proteomes; UP000016930; Unassembled WGS sequence.
DR GO; GO:0031932; C:TORC2 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.10.287.160; HR1 repeat; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036274; HR1_rpt_sf.
DR InterPro; IPR028268; Pianissimo_fam.
DR InterPro; IPR028267; Pianissimo_N.
DR InterPro; IPR029453; Rictor_IV.
DR InterPro; IPR029451; RICTOR_M.
DR InterPro; IPR029452; RICTOR_V.
DR PANTHER; PTHR13298; CYTOSOLIC REGULATOR PIANISSIMO; 1.
DR PANTHER; PTHR13298:SF11; RAPAMYCIN-INSENSITIVE COMPANION OF MTOR; 1.
DR Pfam; PF14663; RasGEF_N_2; 1.
DR Pfam; PF14666; RICTOR_M; 1.
DR Pfam; PF14664; RICTOR_N; 1.
DR Pfam; PF14668; RICTOR_V; 1.
DR SMART; SM00742; Hr1; 1.
DR SMART; SM01303; RasGEF_N_2; 1.
DR SMART; SM01307; RICTOR_M; 1.
DR SMART; SM01308; RICTOR_N; 1.
DR SMART; SM01310; RICTOR_V; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF46585; HR1 repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000016930}.
FT DOMAIN 58..121
FT /note="REM-1"
FT /evidence="ECO:0000259|SMART:SM00742"
FT DOMAIN 211..585
FT /note="Rapamycin-insensitive companion of mTOR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01308"
FT DOMAIN 669..893
FT /note="Rapamycin-insensitive companion of mTOR middle"
FT /evidence="ECO:0000259|SMART:SM01307"
FT DOMAIN 1062..1134
FT /note="Rapamycin-insensitive companion of mTOR"
FT /evidence="ECO:0000259|SMART:SM01310"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 112..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1287..1318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1336 AA; 149515 MW; B1E4D2ED4A81C189 CRC64;
MPALVVEQTS GGGGSSSMRS ISTGASVSST STVNVSTSGP STRDRSGSDH VFDAETQDPV
VALNNQLKVE HRIREGAENL LQMALTDTLR MQVQSELEMA KHKISAITKS IETHSARNQR
KKSLDISGNK RKFTGTPLGQ NVKWREVHDE RDDFRTAMHQ AHSALRTLTS LARPASSSQP
TTPASPSTSP SSSTPPTVAS LSDAAKTRAR IEAMALLIGI LQRNLRVCYE LDIVEVVHAV
LPCLSDKSTK HCRATAYRLI RHSLVDTHTV SRLLEQDLDW YIVKSLARDN KHAVEKEQVI
KLIRTIVEIG SERHDPDEGA ASGTVPLSEA VMRAFIAVAE YPEDPFRPIC VQTLAEILLI
DIDLVARTGG IRILLHALAE GPPEMAPILA SAFLYIIDSP RTRAYLKPGV DLEIALTGIT
DAYGKGTEHV DKMRACTRVI VTMLRTWSGL MYLCLRDKLA VRAIVDGLRI PSLQTREVII
DMFFDLFNIK PPEWHQAFID GRRLTMYRRS KPSIEPGPIL ESPPPSDSLK LTDQYIALLI
LIFTKAGLLD ALTEMFEETT TGSNLSRKAT LLMAELLQKA NRVLPFSIAA KIQALPRVFS
LAADYELGEH RIIGTSALTA IDSYNRHRSR LQPASVRGDS RPRANSIEDA VRRGQKQVEQ
AKIKLAMQMD DKTFQTCLLD TQVMLTKDST KWNFDALQEL VEGPLQNSKR MEEAIKVSRY
MRKLMSFFHP FNHRFSDLQR TTHNVRWIRL GCMLLNVLMS SSDGLRLLSE DEFLGQIVKC
FAQLDPFNGT PTSDPIFSKK RMQETLTYGY FEMLGTLSRR KEGLELLEKA RLFTAFYHVS
ELRSREDLIK AIIENLDYSI DGHSRIVLSK ALTSSYKHIR LFATNHLGDL IRAATVANAW
TLRLLLTQLY DPAPEVRADA VRFLEEACEA VDVLQTVVEM QPTLDHLGEI GHPLLLKFMS
TPTGFRFLYA AGYIDREMDI WFHERNLSYV VHIEVFLSKA FNASADEEDE LMNFDGIVPP
HFYGVMAKTD LGCQVLQEKG HFSEFSLFIR MHGLENEDQD LIMKLKSVLW AVGNIGASEG
GLPFLEEEEI VPTILEIAEK SLVLSVRGTC FFVLGLISST PQGAEILDDY HWEATLSPLG
LPTGLCVPLD VESFTSLPPW ECVSNEGANS TRLKPAETEQ EAEVMTAIYN LANTVIANAA
SRSLARMKAR PEYRHIFSSP SMFYRALHTV SSQRYKLPVR RYIFDLFNID LDADSVKALS
EHAESLTLPP DVAVDEPPEP RVVSFLGRPV NEKQDPDSDE EELDEDDDDR ANFIDKPPVM
SLRPVSRIVG FDRGIE
//
