ID   M2R058_ENTHI            Unreviewed;       372 AA.
AC   M2R058;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=BRCA1 C terminus (BRCT) domain containing protein {ECO:0000313|EMBL:EMD42483.1};
GN   ORFNames=EHI5A_142150 {ECO:0000313|EMBL:EMD42483.1};
OS   Entamoeba histolytica KU27.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=885311 {ECO:0000313|EMBL:EMD42483.1, ECO:0000313|Proteomes:UP000011755};
RN   [1] {ECO:0000313|EMBL:EMD42483.1, ECO:0000313|Proteomes:UP000011755}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KU27 {ECO:0000313|EMBL:EMD42483.1,
RC   ECO:0000313|Proteomes:UP000011755};
RA   Hannick L., Zafar N., Lorenzi H., Ali I.A., Petri W.P., Caler E.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KB445502; EMD42483.1; -; Genomic_DNA.
DR   AlphaFoldDB; M2R058; -.
DR   EnsemblProtists; EMD42483; EMD42483; EHI5A_142150.
DR   VEuPathDB; AmoebaDB:EHI5A_142150; -.
DR   Proteomes; UP000011755; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.10190; BRCT domain; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR022047; Microcephalin-like.
DR   PANTHER; PTHR14625; MICROCEPHALIN; 1.
DR   PANTHER; PTHR14625:SF3; MICROCEPHALIN; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF52113; BRCT domain; 2.
DR   PROSITE; PS50172; BRCT; 2.
PE   4: Predicted;
FT   DOMAIN          215..260
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          273..361
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          1..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..122
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        130..177
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   372 AA;  43057 MW;  2EFCA016FD645769 CRC64;
     MEITSLLDEM NKVGDSTIGA LKEDKKNVPI LSTEEARKKS IDLKEQKEKK QNEDNGEKKS
     SHTKKPIKKL LKSSSSKEEN DNKSKKPKST SSDTKDEKKK TIKKKVTKEE KEEKEKKRKD
     MKKEKKTTTK SKKEKKEKTE ENEDENVDEK KELKRKKTTK VESSEKSHEE KKPRKSDKRT
     KIILSGFDVE HDPFVEEIKT SPFFSVQKAM DDIKLVFVHK SMRTEKVLDA IVKGIPVVNE
     QYLEECEKEN REVEIDPYLL TEAFPGLLVT SQERKNLFKE LSICICGQPK ILATTLSAWI
     ERLGGKITIR PKDADVIICG QLKHHLSLRE KKNDNVQIVA EKWLYDSISS MKVMDYKTYK
     IDVEAIQPEN DE
//