ID M2RAF6_CERS8 Unreviewed; 832 AA.
AC M2RAF6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=CERSUDRAFT_41819 {ECO:0000313|EMBL:EMD41395.1};
OS Ceriporiopsis subvermispora (strain B) (White-rot fungus) (Gelatoporia
OS subvermispora).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Gelatoporiaceae; Gelatoporia.
OX NCBI_TaxID=914234 {ECO:0000313|EMBL:EMD41395.1, ECO:0000313|Proteomes:UP000016930};
RN [1] {ECO:0000313|EMBL:EMD41395.1, ECO:0000313|Proteomes:UP000016930}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B {ECO:0000313|EMBL:EMD41395.1,
RC ECO:0000313|Proteomes:UP000016930};
RX PubMed=22434909; DOI=10.1073/pnas.1119912109;
RA Fernandez-Fueyo E., Ruiz-Duenas F.J., Ferreira P., Floudas D.,
RA Hibbett D.S., Canessa P., Larrondo L.F., James T.Y., Seelenfreund D.,
RA Lobos S., Polanco R., Tello M., Honda Y., Watanabe T., Watanabe T.,
RA Ryu J.S., Kubicek C.P., Schmoll M., Gaskell J., Hammel K.E., St John F.J.,
RA Vanden Wymelenberg A., Sabat G., Splinter BonDurant S., Syed K.,
RA Yadav J.S., Doddapaneni H., Subramanian V., Lavin J.L., Oguiza J.A.,
RA Perez G., Pisabarro A.G., Ramirez L., Santoyo F., Master E., Coutinho P.M.,
RA Henrissat B., Lombard V., Magnuson J.K., Kuees U., Hori C., Igarashi K.,
RA Samejima M., Held B.W., Barry K.W., LaButti K.M., Lapidus A.,
RA Lindquist E.A., Lucas S.M., Riley R., Salamov A.A., Hoffmeister D.,
RA Schwenk D., Hadar Y., Yarden O., de Vries R.P., Wiebenga A., Stenlid J.,
RA Eastwood D., Grigoriev I.V., Berka R.M., Blanchette R.A., Kersten P.,
RA Martinez A.T., Vicuna R., Cullen D.;
RT "Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete
RT chrysosporium provide insight into selective ligninolysis.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:5458-5463(2012).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; KB445791; EMD41395.1; -; Genomic_DNA.
DR AlphaFoldDB; M2RAF6; -.
DR STRING; 914234.M2RAF6; -.
DR HOGENOM; CLU_002472_7_3_1; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000016930; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016930}.
FT DOMAIN 655..671
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 91753 MW; B6AEB741B45C6DB7 CRC64;
MSTIGPTSGY RPSSSRPPTG MSRPWTAQSR PATARPQTAA SARHEASYVV AVLEGRGVAR
EVGIAALDKD TGRVALVQLG DCPTYVKTLH QLHLHSPSLI LVPDTFFSLS DAPLASSAKK
HNTSLLVECL RDEFEHVAVE PVLRKYWNET AGLEFVNQLT VDDDERPATL VAVSTKYYAL
SALSALLKYA ELRLNTRFAA ASLRIRYVQV EGTMMIDPES ARNLELIENA AGKKSRHSLF
GLLNHTYTAM GARLLRVNIL APITVQAAIE SRLDVVEELI QSEARFSEVK NALKALNKLD
LDKLISSVSS AAARVTQMLQ LRNVVQSLPR LAQALGGCRS ELLRIVAEMI SDERLEKIKD
LVGRSLNDDA APARVGGGLE ATNARVYAVR ANYNHLLDVA RETYRENVGD IQMMHRELSQ
AYDLPLRLIF QDNGFVLSLA RKDAQDVELP SEFVNVRVKK GAVVFETMNI KKKNARMKDA
LDETLILSDK IIQDLTAKIL VDIGALYKAS EAVALLDVLW SFAHASIRTH RFFRPEFTGT
LAIKAGRHPV LENVQAAGSV VANDVYCCDA SSFQVVPPID THGLPGKSTY LRQIGLLTVM
AMCGCFVPAE YGSFRVHDAL LTRLSNDDDM EKSLSTFANE MASSAMILGI ATSNSLVLID
EVGRGTSPRE GVGIAHALAE ELIKAKSFVF FATHFYELTT TLSRQPSVVN LHLSVQRTRQ
SASNFGMTFQ YRIVDGAPED QAHYGLDLMR LADLPEDVLT EARRVATNLS ELEAQEQRES
QTNKVAIRRK ALLRLKTQLT QALEHSTLPE EDLVAYLARL QKDVTKTLHE TL
//
