ID M2RTS1_COCSN Unreviewed; 1177 AA.
AC M2RTS1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 13-SEP-2023, entry version 47.
DE RecName: Full=Tubulin-specific chaperone D C-terminal domain-containing protein {ECO:0000259|Pfam:PF12612};
GN ORFNames=COCSADRAFT_78095 {ECO:0000313|EMBL:EMD69994.1};
OS Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and
OS spot blotch fungus) (Bipolaris sorokiniana).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD69994.1, ECO:0000313|Proteomes:UP000016934};
RN [1] {ECO:0000313|EMBL:EMD69994.1, ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
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DR EMBL; KB445637; EMD69994.1; -; Genomic_DNA.
DR RefSeq; XP_007695155.1; XM_007696965.1.
DR AlphaFoldDB; M2RTS1; -.
DR STRING; 665912.M2RTS1; -.
DR GeneID; 19140642; -.
DR KEGG; bsc:COCSADRAFT_78095; -.
DR eggNOG; KOG1943; Eukaryota.
DR HOGENOM; CLU_003043_3_0_1; -.
DR OMA; EPHEAWH; -.
DR OrthoDB; 5477080at2759; -.
DR Proteomes; UP000016934; Unassembled WGS sequence.
DR GO; GO:0048487; F:beta-tubulin binding; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:InterPro.
DR GO; GO:0007021; P:tubulin complex assembly; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR033162; TBCD.
DR InterPro; IPR022577; Tubulin_specific_chaperoneD_C.
DR PANTHER; PTHR12658; BETA-TUBULIN COFACTOR D; 1.
DR PANTHER; PTHR12658:SF0; TUBULIN-SPECIFIC CHAPERONE D; 1.
DR Pfam; PF12612; TFCD_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016934}.
FT REPEAT 356..393
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 924..1094
FT /note="Tubulin-specific chaperone D C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12612"
SQ SEQUENCE 1177 AA; 128547 MW; 4933AC8BBFB72C5D CRC64;
MSAAEDEDLK LQRASALLLP DLEKLLPRLL RKRQQGSTSG SVRHNVRTAD MHKACSLIEP
FQEDPQLLDT HLKTLIPPLV DAYLETISTS TKEDPKDGCL PLSHAICRIL NVFCKVRGEK
VIKGFFNNEP RYLEPILREL EACKDSTNDG PEAALSQSDR PWVRRYVLLL WLSQLLLAPF
PLESMSGLQN SAEASIAPGL KLPTKLPGIA LRVLSICMSQ LRAPTKEKSA AAKLLVRICV
RPDMQKMGLL NSMVSWSLSF FSEVNEEQFD IHQCLGVLSF ISGLLASATN EELGPFLAAT
YQSCRKVLDQ ESLVFIKSSA VARKLVVKSL RNIVLHCLQT TSVIPGLDPT TVLEEVIEFL
LEALADGDTP VRYGASKALS IITLKLDTEM ADEVVEAILG SLTENVYWQS SKRNLSSVNP
LRWHGLTLTL SQLLYRKAVQ TNHLPDVLNA LLLSLGFEQR SPTGGSIGTN VRDAACFGIW
ALSRRYATAD LLVVDTASIR ASEHLKSLNV PQVLAIELVV AACLDPAGNI RRGSSAALQE
LIGRHPNTIE EGIPLVQMVD FHAVGLRQRA MCDVAIKAGD LSSLYWEALF EGLLDWRGTG
SLDSESRLFA AEAVGSLSKG RSLAVVQRMS GQVRNTLSAL RPRQVEERQG LVSTLAALVD
TARTLIDNSG DGALYASLSD LWALLLSDLK LEDKAFTSPA LRPQFTASSI CAFIAAMATF
TTDCSSSIKS SEIPTEEVCR LFDLCLTRHE QPVLDGIAVT APAVILLLSK TPKVDTIEVV
SSWLTRLENE ASYNGLRCSG HAVALGAAYA NLTNLPADTK REEIQRRIVK VLTFRCTAAV
AIEARTVALR ALGDLLASKS SASYHLAPDA ETQVGRALHI ALNDYTITER GDVGALVRLE
ALNTAHLAWT SGLLSSTHEP CGREIYADVL RLSLEKLDKM RVKASQVLHH ALDPSALDAG
VSSKSFFLSA LAPLQSSADT IIKEAICVGF VSSAGMGSES VVQNSRMALL DFVDTLPSSS
DAGDQYSLLD LATTFLTLLK SHLDNDRILL PLLEVLAFLF DMHVMHRLTT TSFSFRTLLS
YAQKSHFKSS HVHKLHLALD MYRGLGSVPV TREETLRKVT SMLLHPFPKI RVTAAETLWF
LMGEEGLKRH DWSLPSKILK PAVDGIRAAV VAGEEAE
//
