ID M2SPU8_COCSN Unreviewed; 1077 AA.
AC M2SPU8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 03-MAY-2023, entry version 38.
DE RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0000259|PROSITE:PS51384};
GN ORFNames=COCSADRAFT_36914 {ECO:0000313|EMBL:EMD64335.1};
OS Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and
OS spot blotch fungus) (Bipolaris sorokiniana).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD64335.1, ECO:0000313|Proteomes:UP000016934};
RN [1] {ECO:0000313|EMBL:EMD64335.1, ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; KB445643; EMD64335.1; -; Genomic_DNA.
DR RefSeq; XP_007699820.1; XM_007701630.1.
DR AlphaFoldDB; M2SPU8; -.
DR STRING; 665912.M2SPU8; -.
DR GeneID; 19138848; -.
DR KEGG; bsc:COCSADRAFT_36914; -.
DR eggNOG; KOG1158; Eukaryota.
DR HOGENOM; CLU_003662_1_0_1; -.
DR OMA; MIVAVNW; -.
DR OrthoDB; 5488444at2759; -.
DR Proteomes; UP000016934; Unassembled WGS sequence.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd06207; CyPoR_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR19384:SF109; SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR Pfam; PF01558; POR; 1.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000016934}.
FT DOMAIN 687..918
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1077 AA; 119799 MW; 169DDF7BEB19BD3C CRC64;
MHFQQTDSAG PGAEQNAPKE FTKKSSSLPF GQDLSYQSIS GPTYLTAQTL VQQVAYALSD
KIFAYSAESF DLDVAVKHWQ EQGEKNAFGY QTGVSSLETR TGAGAIALGY MFSKDFDLKK
RHIPQSIIAS SSTLTHLRSS LDQLAALYSV ANPLTAHIAA VDYSANASAG LVTDYVSSLS
LAEDLGLGLV CSPSVFESQH MALFATLLSS VIPTIHTYDG ISVGRETARL VDTLDQARLY
NSYEAVLKAV SDVDKKHSDT AGRVLRLLQA FNDELGEDYK LFDYYGHEEP ESVLVVFGTV
EASLTAQVAT ALSKEGEKVG AINVRVYRPF VEEAFLEALP KSTRRIAVLG QVKDETAVLD
PAEYSRLYAD VLAAVQFTLD RNVEVTDVKY SREQVWTPSN FLDAFRQIHA EKEGIEARSF
IDILNNADVK QYSFWNLDES LAANAPAVIG KLFSTDSSKN VFVRNGHDNL VQGGVTRTDI
RNADYTIEAP YAVEQADVAF VGDEAILKAF DVLNSVKPDG SIIVKLPGVK NEDIEKKLSP
AFRKTLVNKD IELFVLDPAL SEAVAEDESL ESFLTQLAFL KVAREDLLTS GLSKLATING
SLELFEKLAA QLENALREVE VPTTWGTAED AEPISLPSDI NVTSFAPFER TEPEPPTLLK
DWQVAAKGFT FKEAYGTSNQ VRPDLGIKTS IVHVKERRRL TPQNYDRNIF HIEFDLGDSG
VTYAIGEALG IHAENDEAQV DEFIKWYGLN PNEIVEVPSR EDPNVLVNRT VYQSLLQNVD
IFGRPPKRFY EALAEFASDE AEKRELLQII SPEGATEFKR RAEVDTITYA DILLEFPSAH
PSFHEIVRIV SPMKRREYSI ASAQHVTPNS VSLLIVTVNW TDPKGRDRFG QATRYLNSLK
VGSPVTVSVK PSVMKLPTKT TAPIIMAGLG TGLAPFRAFV QERAYQKQQG HEIGEVLLYM
GSRHQREEYL YGEEWEAYQD AGIITLIGRA FSRDQPQKIY IQDRMRESLK DIRRSYLEKE
GSFYLCGPTW PVPDVTEVLQ EALEVEHKVK NPAAKKIDSR KEIEKLKDEG RYVLEVY
//
