ID M2SVT1_COCSN Unreviewed; 897 AA.
AC M2SVT1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Transferrin receptor-like dimerisation domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=COCSADRAFT_183877 {ECO:0000313|EMBL:EMD60952.1};
OS Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and
OS spot blotch fungus) (Bipolaris sorokiniana).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=665912 {ECO:0000313|EMBL:EMD60952.1, ECO:0000313|Proteomes:UP000016934};
RN [1] {ECO:0000313|EMBL:EMD60952.1, ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ND90Pr / ATCC 201652 {ECO:0000313|Proteomes:UP000016934};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; KB445649; EMD60952.1; -; Genomic_DNA.
DR RefSeq; XP_007703313.1; XM_007705123.1.
DR AlphaFoldDB; M2SVT1; -.
DR STRING; 665912.M2SVT1; -.
DR GeneID; 19133430; -.
DR KEGG; bsc:COCSADRAFT_183877; -.
DR eggNOG; KOG2195; Eukaryota.
DR HOGENOM; CLU_005688_1_0_1; -.
DR OMA; YPRKDGR; -.
DR OrthoDB; 67337at2759; -.
DR Proteomes; UP000016934; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF71; CARBOXYPEPTIDASE TRE2, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10650)-RELATED; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000016934};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 166..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..403
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 506..681
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 766..895
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 897 AA; 100158 MW; D536A9C22A048D0E CRC64;
MSDEKHNYVR EPSPPPIPTY DEATSSRNAP ARLGPNEISD DAERQGLLTP DVRTQSDSRR
RNGYYQPPSV QSVDDGDSDL GSPVRESQDE DLRQTMEEME ILDPEAVEEG RSRRNRTRNR
FSKRFNSIRH SLSNWNLPRI PWPSWRPNFS AVTDHMPTIS EEYRPGWAMF ARLLGLFVIV
ILVYFLVASE VVPMGGGFGT PFNPEWIRQT AVEGVESWRI EKNLEYITSY DHIGGTEGSY
VLGQWIEGKF KDANMDTFTH DEYFVYMNYA KKNGRKVAIV NPPDKAWEAK LEEPSVFNPP
KAQTPAYHAM SASGNATGPL IYVNYCHKKD FKRLWDSGID AQGAIVLCRY YGTQPDLAMK
LRSAQNAGVA GVLVYSDPAD DGFKKGNPWP DGKWRPGESV QRGSVAQTNM IIGDILTPGK
PSLKKMERMS RDKNPAVPKI PSLPLSWKDA QKLLQSLKGV GEELPDEWVG GVPDIGDKWY
SGHPEKSPKV YIQNNQDEVE QQRITNVFGS LKGTEDPGRK IIIGNHRDSW CFGAADPGSG
TAVMLEVVRV LGELRAQGWR PLRTIEFASW DAGEYNRIGS TEHVEANVDA LREGAIAYLN
LDVGVTGDKL WANGSPIFQH AWSRILDRLS DPHENKTLRE LWDASNSKIG NLGAGSDYVA
FQNIAGTSSL DFGFSASTSP KDGPAHPLSH SCFETLSWMR KYIDPSFSYH TLLTQLTLLL
ILELAQEPIL PLKLDDYASA LQQQGQSLLD WTEKISGGAD YDIGIFQPLV DALSMLKKRT
EAFGAWEQSW YNQVYATGGF ESSGVTMQRV RHNAKIAAVE SDMLDLARGK EDKGPHGLPN
RDQFKHVLFA PDLENGLEAS VFPFAREAIA TKDWKKAAEA IKMTADVLNR AGERLGQ
//
