ID M2UIM8_COCH5 Unreviewed; 597 AA.
AC M2UIM8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Protection of telomeres protein 1 {ECO:0000256|ARBA:ARBA00015253};
DE Flags: Fragment;
GN ORFNames=COCHEDRAFT_1143433 {ECO:0000313|EMBL:EMD87833.1};
OS Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) (Southern
OS corn leaf blight fungus) (Bipolaris maydis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris.
OX NCBI_TaxID=701091 {ECO:0000313|EMBL:EMD87833.1, ECO:0000313|Proteomes:UP000016936};
RN [1] {ECO:0000313|EMBL:EMD87833.1, ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
RN [2] {ECO:0000313|Proteomes:UP000016936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C5 / ATCC 48332 / race O {ECO:0000313|Proteomes:UP000016936};
RX PubMed=23357949; DOI=10.1371/journal.pgen.1003233;
RA Condon B.J., Leng Y., Wu D., Bushley K.E., Ohm R.A., Otillar R., Martin J.,
RA Schackwitz W., Grimwood J., MohdZainudin N., Xue C., Wang R., Manning V.A.,
RA Dhillon B., Tu Z.J., Steffenson B.J., Salamov A., Sun H., Lowry S.,
RA LaButti K., Han J., Copeland A., Lindquist E., Barry K., Schmutz J.,
RA Baker S.E., Ciuffetti L.M., Grigoriev I.V., Zhong S., Turgeon B.G.;
RT "Comparative genome structure, secondary metabolite, and effector coding
RT capacity across Cochliobolus pathogens.";
RL PLoS Genet. 9:E1003233-E1003233(2013).
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the telombin family.
CC {ECO:0000256|ARBA:ARBA00008442}.
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DR EMBL; KB445581; EMD87833.1; -; Genomic_DNA.
DR AlphaFoldDB; M2UIM8; -.
DR STRING; 701091.M2UIM8; -.
DR eggNOG; KOG4757; Eukaryota.
DR HOGENOM; CLU_016663_1_0_1; -.
DR OMA; WEPHASF; -.
DR Proteomes; UP000016936; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043047; F:single-stranded telomeric DNA binding; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR028389; POT1.
DR InterPro; IPR032042; POT1PC.
DR InterPro; IPR011564; Telomer_end-bd_POT1/Cdc13.
DR PANTHER; PTHR14513; PROTECTION OF TELOMERES 1; 1.
DR PANTHER; PTHR14513:SF0; PROTECTION OF TELOMERES PROTEIN 1; 1.
DR Pfam; PF02765; POT1; 1.
DR Pfam; PF16686; POT1PC; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022895};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016936};
KW Telomere {ECO:0000256|ARBA:ARBA00022895}.
FT DOMAIN 7..111
FT /note="Telomeric single stranded DNA binding POT1/Cdc13"
FT /evidence="ECO:0000259|Pfam:PF02765"
FT DOMAIN 183..324
FT /note="Protection of telomeres protein 1 ssDNA-binding"
FT /evidence="ECO:0000259|Pfam:PF16686"
FT REGION 336..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 597
FT /evidence="ECO:0000313|EMBL:EMD87833.1"
SQ SEQUENCE 597 AA; 68002 MW; 32CC7B1894D0FA50 CRC64;
MQLPNGFTAI KDATSEGQSV NLIGILVACD GPRSSKGLDH VLSFTIQDDF ADVSASTYSS
INGRMFKPPN KFPKISGIGD ILILRNAKLK PWVGRMECIG DRQFTHMTVF PSSMIPVPEL
SHAYQAGSQK LPCDSSWGAP QPTIPEQMAV IHLKHASSGS SQQIRQHATT AAFKTQTKKR
DCLIKDLQFN TFADIRAQVV NIYHYHGQAD LKVTDYTPNE SMFYYADPEK EDSFHIADRH
WKGPYGYLTL SVTLYEENAN WAREHLAVGD YVFIRNMRVK LSARSKLEGV VHQDRVNKSQ
VDIRILNNAS EIAEIDSRRK EYESKRGGLT AFEKIHSEAK KPSAKTSNSK KLAKRERLRA
EKEAEQQEIE KKAREWEVER SGLNNNIRCA HVDMKSSTIS EIIHNPHLRV RTLEKCNDYE
LPFVNCRYRS RVRVVDVFPP KLELFAHSLN DPNWAKRSEK QHADSTCPKE RWEWGFVLLL
EDAEAPQGGV SEKLRVVVNN SSAQYLLKLN AQDLKNNSKV LRQLEHKLFL LWGNLMELKT
ELRAKGSDLP LPPGDNRLQN KPFDTCIEEY GCQVPVTEDH PFGYQRMHNL TLTTIMD
//
