ID M2VZ51_GALSU Unreviewed; 569 AA.
AC M2VZ51;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=proline--tRNA ligase {ECO:0000256|ARBA:ARBA00012831};
DE EC=6.1.1.15 {ECO:0000256|ARBA:ARBA00012831};
GN ORFNames=Gasu_39770 {ECO:0000313|EMBL:EME28601.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME28601.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
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DR EMBL; KB454518; EME28601.1; -; Genomic_DNA.
DR RefSeq; XP_005705121.1; XM_005705064.1.
DR AlphaFoldDB; M2VZ51; -.
DR STRING; 130081.M2VZ51; -.
DR EnsemblPlants; EME28601; EME28601; Gasu_39770.
DR GeneID; 17087460; -.
DR Gramene; EME28601; EME28601; Gasu_39770.
DR KEGG; gsl:Gasu_39770; -.
DR eggNOG; KOG4163; Eukaryota.
DR OMA; HMFAQWV; -.
DR OrthoDB; 2733051at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004827; F:proline-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00862; ProRS_anticodon_zinc; 1.
DR CDD; cd00778; ProRS_core_arch_euk; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR Gene3D; 3.30.110.30; C-terminal domain of ProRS; 1.
DR HAMAP; MF_01571; Pro_tRNA_synth_type3; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR004499; Pro-tRNA-ligase_IIa_arc-type.
DR InterPro; IPR016061; Pro-tRNA_ligase_II_C.
DR InterPro; IPR017449; Pro-tRNA_synth_II.
DR InterPro; IPR033721; ProRS_core_arch_euk.
DR NCBIfam; TIGR00408; proS_fam_I; 1.
DR PANTHER; PTHR43382:SF3; PROLINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL; 1.
DR PANTHER; PTHR43382; PROLYL-TRNA SYNTHETASE; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF09180; ProRS-C_1; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR SMART; SM00946; ProRS-C_1; 1.
DR SUPFAM; SSF64586; C-terminal domain of ProRS; 1.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:EME28601.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:EME28601.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680}.
FT DOMAIN 99..364
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 569 AA; 65791 MW; 10B5225B980315B0 CRC64;
MGLSNQWNRC ASLRCLFLVH SSWKNDSKFT IHHSWNRHLA CHHIGRAQKW SYKNRIPVIT
FSCLATDVSS KSDNKITPRS EDYSAWYLHV IQAAQLADQS AVKGCLVIRP YGYAVWELLR
DHLDKLIKET GAQNAYFPLF IPQSFLSKEA EHVEGFAKEC AVVTHHRLRL NTNSTLEPDP
EAMLEEPLIV RPTSETLIWN MFQKWISSYR DLPLCINQWA NVVRWELRTR PFLRTTEFLW
QEGHTAHTNA KEAMDKAKEM LNVYTQLCEE LLAIPVIKGC KSPSERFAGA EETFTIEAMM
QNGWALQSGT SHFLGQNFAK AFQVYYTDTS SQEQLVWATS WGASTRLLGA LIMTHSDDIG
LVLPPKVAPI QVIIIPIWKS QVDKEDTLRV SQKLLEQLKG AQIRAKLDDR DYIRPGSKYF
EWERKGIPLR IEIGPRDVVD GVVTIASRIG NQKKYALPCN ESLTMHIQQQ LENMQRCLFQ
QAKERMDSRT FRNVSFDEMK RRLNEKDIQK QGFFLVPWKC NAIHEERIKA ETKATIRCYP
FDMQHLVKNE KCFYSGEPAT HMALFARAY
//
