ID   M2XKK4_9PSEU            Unreviewed;       256 AA.
AC   M2XKK4;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Regulator of SigK {ECO:0000256|ARBA:ARBA00030803};
DE   AltName: Full=Sigma-K anti-sigma factor RskA {ECO:0000256|ARBA:ARBA00029829};
GN   ORFNames=H074_10355 {ECO:0000313|EMBL:EME61566.1};
OS   Amycolatopsis decaplanina DSM 44594.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Amycolatopsis.
OX   NCBI_TaxID=1284240 {ECO:0000313|EMBL:EME61566.1, ECO:0000313|Proteomes:UP000054226};
RN   [1] {ECO:0000313|EMBL:EME61566.1, ECO:0000313|Proteomes:UP000054226}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44594 {ECO:0000313|EMBL:EME61566.1,
RC   ECO:0000313|Proteomes:UP000054226};
RX   PubMed=23558534;
RA   Kaur N., Kumar S., Bala M., Raghava G.P., Mayilraj S.;
RT   "Draft Genome Sequence of Amycolatopsis decaplanina Strain DSM 44594T.";
RL   Genome Announc. 1:E0013813-E0013813(2013).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC       Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EME61566.1}.
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DR   EMBL; AOHO01000045; EME61566.1; -; Genomic_DNA.
DR   RefSeq; WP_007029980.1; NZ_AOHO01000045.1.
DR   AlphaFoldDB; M2XKK4; -.
DR   PATRIC; fig|1284240.4.peg.2100; -.
DR   OrthoDB; 153510at2; -.
DR   Proteomes; UP000054226; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.10.1320; Anti-sigma factor, zinc-finger domain; 1.
DR   InterPro; IPR018764; Anti-sigma_K_RskA.
DR   InterPro; IPR041916; Anti_sigma_zinc_sf.
DR   InterPro; IPR027383; Znf_put.
DR   PANTHER; PTHR37461; ANTI-SIGMA-K FACTOR RSKA; 1.
DR   PANTHER; PTHR37461:SF1; ANTI-SIGMA-K FACTOR RSKA; 1.
DR   Pfam; PF10099; RskA; 1.
DR   Pfam; PF13490; zf-HC2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        97..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          11..37
FT                   /note="Putative zinc-finger"
FT                   /evidence="ECO:0000259|Pfam:PF13490"
SQ   SEQUENCE   256 AA;  26846 MW;  3C062B9FA1076B49 CRC64;
     MTMPEMHTLT GAYAVDALSE VERAQFQRHL AECASCAQEV LELQMTATRL GAALAEDPPP
     ELKHRVLAEA MATRQQPPKT RFGTGERVKD RRRAPRWAIA AVAAAVVGLA GTAVFGGIAY
     DNHSQLTAAR ERAAVYADRY APVADVLAAA DLRTGHAETS AGGGGTVMMS RAKDRLVFMA
     AQLPKNEPGR TYQAWLMYPG TAPKPAGLIS GGQDGALLVA DGLGGAEKFA LSVEQAGGSP
     TGSPSKDVVM VMSMPT
//