ID M2XRV7_GALSU Unreviewed; 705 AA.
AC M2XRV7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
DE Flags: Fragment;
GN ORFNames=Gasu_61750 {ECO:0000313|EMBL:EME26174.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME26174.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; KB454586; EME26174.1; -; Genomic_DNA.
DR RefSeq; XP_005702694.1; XM_005702637.1.
DR STRING; 130081.M2XRV7; -.
DR EnsemblPlants; EME26174; EME26174; Gasu_61750.
DR GeneID; 17085164; -.
DR Gramene; EME26174; EME26174; Gasu_61750.
DR KEGG; gsl:Gasu_61750; -.
DR eggNOG; KOG0261; Eukaryota.
DR OrthoDB; 169836at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 2.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 209..465
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EME26174.1"
SQ SEQUENCE 705 AA; 80539 MW; 1A84B1B95FFB655D CRC64;
EEAAILDEWE VDGDEHLAVT DDDEAFNFXT XRLFTSEEIQ KMAVCEIHEV DLSKVFGTVT
DSRXGPVDFQ TPCSTCLRTF KDCPGHYGYI DLESCPILHP LFLKEFSYIF KSICHSCCTP
FLSSAEISYX EKCGNEVSLK SIAGWSEYSR CANDCPPNKI FEXKDGRLYF VSNEGKLYER
SXSSAKKILE AVDERYWXDV FRMEYTNPAS FIIDKLXVIP SQSRPPILLN GEVTDHDLTK
CYSDIVRHKF HQHYDXXTKS IYQLFDGFNG IGRRTXGIKQ RIQGKKAVXR KNXMGKRVNY
CCRSVAAPDP TLDVDEVRVP KVICSKFLHE AQKXTESNFD YWKELFQKGQ ASGGPLEIGR
YARRHXMEGD SVTLNRQPTL YKQGFMVHKV RXGEELVIRM HLSXTPLYNA DFDGDEVSVM
FSPNKNVQQE XRQKXSVSNY IISDHTGKVS VSLSYDALSG LYKMPKEQRP PPFDSLDKIS
KSTVKQAIYK YHQENGKDAT IRXISDTSRA VLEFLEHNIX SASYHNLLEL MDSSNKQQIX
EEMRDNFKKA NSXEERIGAL SFRFPRIEKQ NDFXXMVDSE TKGTFFHLSQ XSYFXGQQFI
NGTVFLPDAE TNRVTPWDSF EEDLSNPELY GFISHSFLEG LSPREMFFHA NGGREGXVDT
ACRTSEVGNL QRNLCKSIEN YFLDEKGLVV NSLGEVLSFS DSTLY
//
