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Database: UniProt
Entry: M2Y228_GALSU
LinkDB: M2Y228_GALSU
Original site: M2Y228_GALSU 
ID   M2Y228_GALSU            Unreviewed;       856 AA.
AC   M2Y228;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   07-JUN-2017, entry version 19.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=Gasu_28510 {ECO:0000313|EMBL:EME29854.1};
OS   Galdieria sulphuraria (Red alga).
OC   Eukaryota; Rhodophyta; Bangiophyceae; Cyanidiales; Cyanidiaceae;
OC   Galdieria.
OX   NCBI_TaxID=130081 {ECO:0000313|EMBL:EME29854.1, ECO:0000313|Proteomes:UP000030680};
RN   [1] {ECO:0000313|Proteomes:UP000030680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX   PubMed=23471408; DOI=10.1126/science.1231707;
RA   Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA   Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M.,
RA   Carr K., Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E.,
RA   Oesterhelt C., Lercher M.J., Weber A.P.;
RT   "Gene transfer from bacteria and archaea facilitated evolution of an
RT   extremophilic eukaryote.";
RL   Science 339:1207-1210(2013).
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; KB454505; EME29854.1; -; Genomic_DNA.
DR   RefSeq; XP_005706374.1; XM_005706317.1.
DR   EnsemblPlants; EME29854; EME29854; Gasu_28510.
DR   GeneID; 17088620; -.
DR   Gramene; EME29854; EME29854; Gasu_28510.
DR   KEGG; gsl:Gasu_28510; -.
DR   KO; K02154; -.
DR   OMA; FILRANH; -.
DR   Proteomes; UP000030680; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000030680};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Hydrolase {ECO:0000313|EMBL:EME29854.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    436    460       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    481    498       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    566    584       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    596    619       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    671    693       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    796    818       Helical. {ECO:0000256|RuleBase:RU361189}.
SQ   SEQUENCE   856 AA;  97947 MW;  AC4FA1A227220BEC CRC64;
     MGSLCRSQEM IKLRLFVEKS VAHETMVELA ELGVFQLNDL NEEKSTFQRT FAADVRLCDE
     MQRRLRFLEE QVDFQLEEQR LEDTITVEAL QSLQLEELAR YLCDLEGNVT EMNSHWGALK
     AEERKVAEHA ILLQAGAKFF EDAPKVSLSE YGTTIMSPDP EHRSINIPRS SAKNDEETTS
     LLGVSKTGRD GMEESILGYY AGFISFENIH PFERILFRVS RGNAYLRLVS LDEISSVNIR
     FEKMENEWGR KRVFIVFFPG VALGTKILKI CEAFSVSLYN LPEGEVERYR LLQSLEQEFN
     DLQTVIASTQ SQREEAFREI ALQLSLWKEK VRREKTIFHA LNLLNYDTSN NVYIADGWCP
     LDEYGNLQDC LSRAQKRAHA QSPTVVEVIK YPKDTPPTFY KLNKFTIVFQ NVVESYGVPC
     YQELNPAPFT IVTFPFLFAI MFGDIGHGML MTLVAAILIF KEKQLGGRKL NELVQTCFDG
     RYMILLMGLF SVYTGFIYNE CFGVSLNLFQ TRWKFTDASS LACGVDSCAD ALSNKPPLDI
     YPFGFDPVWS RAQNGLSFLN SYKMKLSIIV GVTQMLLGIV LSYFNASFFR SGLDIWYVFV
     PQLLFMSCTF GYLVLLIFIK WLTNWNAPSC LSDSRCRPPD LKNTLIGLFM TPYKVAEDAK
     LFPFQGEIQS VLLLIAIVSV PWMLLPKPLI LLYRHRKSKI VIGNEEQRPL LDKELSTQTN
     NHVQGGTHSD MNKKEEESFD FGEVMIHQLI HTIEFVLGAV SNTASYLRLW ALSLAHSELS
     LVFLEKVLYN TISLEHPIAI MIGFLLWAFL TIGVLCLMES LSAFLHALRL HWVEFQNKFY
     NLQGEGRKFI PMSFSI
//
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