ID M2Y8E3_9PROT Unreviewed; 483 AA.
AC M2Y8E3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:EME69321.1};
GN ORFNames=H261_13935 {ECO:0000313|EMBL:EME69321.1};
OS Paramagnetospirillum caucaseum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Magnetospirillaceae; Paramagnetospirillum.
OX NCBI_TaxID=1244869 {ECO:0000313|EMBL:EME69321.1, ECO:0000313|Proteomes:UP000011744};
RN [1] {ECO:0000313|EMBL:EME69321.1, ECO:0000313|Proteomes:UP000011744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO-1 {ECO:0000313|EMBL:EME69321.1,
RC ECO:0000313|Proteomes:UP000011744};
RX PubMed=24723706;
RA Grouzdev D.S., Dziuba M.V., Sukhacheva M.S., Mardanov A.V., Beletskiy A.V.,
RA Kuznetsov B.B., Skryabin K.G.;
RT "Draft Genome Sequence of Magnetospirillum sp. Strain SO-1, a Freshwater
RT Magnetotactic Bacterium Isolated from the Ol'khovka River, Russia.";
RL Genome Announc. 2:e00235-14(2014).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EME69321.1}.
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DR EMBL; AONQ01000037; EME69321.1; -; Genomic_DNA.
DR AlphaFoldDB; M2Y8E3; -.
DR STRING; 1244869.H261_13935; -.
DR PATRIC; fig|1244869.3.peg.2808; -.
DR eggNOG; COG1032; Bacteria.
DR Proteomes; UP000011744; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 6..140
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 189..425
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 483 AA; 55358 MW; 9D41DCB4A4D9FE4C CRC64;
MGYGINTKKS KKKIYGYTPP LGLGMLARVA KDYGCDVTVN DAGPLGDDFE SLIRKIVEFK
PDIVGFSVFT ANFAQAVESV RLVREHPALR DTLVVIGGPH VYTFREKTLA DIPADVAVYG
EAEADLIELL EFYDGTRASL EEVNGLFFRS EQGIVQTQET HSSRSLDHFG FPDWDQFDFS
LYRNIPGQIR RYPMTSMVTS RGCPFRCNFC FQAGRFADKY RRYSPELVID EIQRLQSRYG
IREIQFWDDI FFINKKWVET FCRLIQEKKI DITWSGYARV DLISPELLRM ARDSGCWNIF
YGFETGTQEM LDFLEKKATL EQAVNASRWT REAGIISRGS FMLGLPNETP ELGEKTIDFA
IQLDPDYANF NIFFPEPGTG LYDLAVQSGR MLSGEYLGRS VPVYLPDGYQ SIDQIRDLQK
KAFRRFYFRP SYIAKRISRI RSWSEIGQYV DGAMMLLSMN KPKIPFAFAT ESSKTGQKGR
NVF
//
