ID M3ASX1_SPHMS Unreviewed; 892 AA.
AC M3ASX1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=CRAL-TRIO domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SEPMUDRAFT_152230 {ECO:0000313|EMBL:EMF08609.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF08609.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF08609.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF08609.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
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DR EMBL; KB456271; EMF08609.1; -; Genomic_DNA.
DR RefSeq; XP_016756730.1; XM_016907315.1.
DR AlphaFoldDB; M3ASX1; -.
DR STRING; 692275.M3ASX1; -.
DR GeneID; 27904452; -.
DR eggNOG; KOG4406; Eukaryota.
DR HOGENOM; CLU_016267_0_0_1; -.
DR OMA; REACGQT; -.
DR OrthoDB; 3030820at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016931}.
FT DOMAIN 37..206
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 223..436
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 11..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..506
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 892 AA; 97544 MW; 80EA7EF355502214 CRC64;
MRSALRTALQ ADAQRRAGRD RSNSLSTVPP ATDSDDYVPE LAAIAATILY RSPLPSSEGR
PVYVLNSAAF PDAFEVDYDS LLSYVLARLP GEDELLSGTE YEIVFFAGGP LDSATAEKKQ
GPATGWYLQA YHVLGRALRK KLAMLYIVHP RTWVRVLLNV FGTVVSPKFR RKILHVNCLT
QLAVHIPIEK LLIPPSAYLQ DRKYSPDIFS PFVTGRRAFG VKHPLPKNIT TGKTRLPRVL
RETTTFLLEP SNVKTEGIFR IPPHSTLTSI LKEAYDRGQQ WIVWKEMDAS YSQPGLDKST
IDEIRSEDTY GVHLAASMIK TWYRELREPI FHESSYAMLR ERYNDPDVQV TPEDLVDIML
DSSPVSPLSA TAREILTRHL LPLLSVVALH EPDNKMTAEN LAICFSMCLV CGTDQMADAK
VSTIVKRILQ AAITMWPQLR TGLGLDESSF YADLQAPDDP KEYEDPLEQL CRPSSYSEDD
PKSQIGHRIS MNDSDGSDSS NGQPPALPPR RRSRAQSFKA ALAPHIPNVE LPRLPKRKPA
PYREPSPGPA VAQQHTTDVT TMGEPPRYSS IFDREGRHLS RPESPGSFVQ VPADGFAPPR
RSDSSFDMME EVKQQKPRRR PVSGAPVEAI PSGPASAEGI GRTLPGSLAD VPKRKPVSRQ
TSVKGENSQR DGSVLQNCSQ STNTSTSTIT PDSMPSRPMP SMPAGTNAVL AEMAARQAAN
NLVQNNVTDT EAVSVNSSTV TPVQHTTPAD LAVKMPQSTT STPVVEGPFR KPSWPASAKQ
QGPGIQSLAK PILPTRTLNT IVPAVSGPDG TGGPAPGVPK PRAPSAGLLN RMSSWENRGN
PDSSPSQSSA MLEPSKLNLK KSSVDDLRRL YEERATTAST LVQIGRSSSS NQ
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