ID M3C3Y1_SPHMS Unreviewed; 739 AA.
AC M3C3Y1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Voltage-gated potassium channel {ECO:0000313|EMBL:EMF14946.1};
GN ORFNames=SEPMUDRAFT_161231 {ECO:0000313|EMBL:EMF14946.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF14946.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF14946.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF14946.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|RuleBase:RU003857}.
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DR EMBL; KB456261; EMF14946.1; -; Genomic_DNA.
DR RefSeq; XP_016763067.1; XM_016907924.1.
DR AlphaFoldDB; M3C3Y1; -.
DR STRING; 692275.M3C3Y1; -.
DR GeneID; 27905061; -.
DR eggNOG; KOG1418; Eukaryota.
DR HOGENOM; CLU_013394_1_0_1; -.
DR OMA; DWWFAST; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF342; POTASSIUM CHANNEL PROTEIN; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:EMF14946.1};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 28..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 506..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 217..300
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 455..530
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 352..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 572..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 739 AA; 83046 MW; 883F2E0DA874BA45 CRC64;
MHPKRSSTRL GGSFHFRQWN EDDDQQDWWF ASTAIPLLAA TIGPLASVFS LAALITSWRM
CLVSTATSAT AAAICSWDGD TTLLVTQLQG HDFADPTWCY TLNLVSLIVG FIGNFFLLCN
FTNRIRYVIA LPVTMLCWYG AAGILCGITW SMQIYVPPLR PQQTYTQGFW YGVLAACMYL
GCATILMVNM LGFALGHYPQ HFTLTDSQRT LILQTMLFFL WLAAGGGIFT AVERRYGDYD
EGNFPWSFVN SLYFSDVTIL TVGFGDLYPS SDVGRGLVFP YSVGGIVMLG LMVSSIAGFA
RELSSEKVVK RHVEKTRART MDRTVTSSLE LERKQMPPGD GRLISTPAFC HAEEDKSKEK
EEEEEQRTIN FPDDVDHPPS GRGPLSWTGT YIGSLRRAAG STWALPPQRL APRKPKLLLL
REEKDRFELM RRIQKSTSRF KRWYALLLSV AAFGVLWCGG GVVFWQAEKN TENEMTYYKA
LYFAYVSLLT IGYGDLSPKS NAGRPFFVFW SLLAVPTMTI LVSDLGDTVV KKFKNGTSGV
ADFTVLPQKG VWRAILNRQP WLLKTLQSRK AGKEMRRKEE EGLPYGPEPD AEVATNPTTT
TIDQLAVEQT TDAQLAAELP KAIKRVARHV TNREKSRYSY EEWVEFTRLI RFTVDKRQDD
EQEDQRGMVE WDWIGEDSPM MANTSEAEFV LDRLCESLSR YVRRMEKTLA SAGDGNKVAV
DAGNDLSGGS EHLSQTLGE
//
