ID M3C4K0_SPHMS Unreviewed; 1008 AA.
AC M3C4K0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=DNA repair protein rad5 {ECO:0000313|EMBL:EMF15226.1};
GN ORFNames=SEPMUDRAFT_147156 {ECO:0000313|EMBL:EMF15226.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF15226.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF15226.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF15226.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB456261; EMF15226.1; -; Genomic_DNA.
DR RefSeq; XP_016763347.1; XM_016904120.1.
DR AlphaFoldDB; M3C4K0; -.
DR STRING; 692275.M3C4K0; -.
DR GeneID; 27901257; -.
DR eggNOG; KOG1001; Eukaryota.
DR HOGENOM; CLU_000315_2_5_1; -.
DR OMA; KVEPWSN; -.
DR OrthoDB; 200191at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd18008; DEXDc_SHPRH-like; 1.
DR CDD; cd16572; RING-HC_SpRad8-like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014905; HIRAN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45626:SF22; DNA REPAIR PROTEIN RAD5; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF08797; HIRAN; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00910; HIRAN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 328..540
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 721..766
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 842..998
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 195..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 113615 MW; 8EF7F0894C67635F CRC64;
MPPMRYIGAL GVAGWTTRSG VSLRADDVVK IQRVRQAPKL KMGKGGKTQQ VSRRTEDVIV
RFTDKNGTEI GRLEKDSALW IGALIDQNVC HFEGHCVFAP ERIKTNDTVY IQLRCFLLRF
VFETGNLIKS VDDNRSAGFL ETAETSQERD LRLRQIGLVK LFSEINLQPA SVNEVTAKHK
REGILQAAEV AEQFDRVGSN KKSSQDKENG GSSPPSDDNE KEEGEELEQD QLDSLYKKAQ
SFDFNTPTAE PASTFVMDLR KYQKQALYWM LQKEHRRNDV KQEQSMHPLW EQYLWPAKDA
DDKDLHMVEG QDCFYVNPYS GELSLDFPIQ EQNCLGGILA DEMGLGKTIQ ILALIHSHRS
PEHEGIVHDQ IDVEVDAVSS LKRQTMASKT VKRAPATTLV VAPMSLLAQW ASEAEKASRS
GTLKVLVYYG SEKEANLQTL CCGSDLSSAP NVIITSYGTV LSEFNQVVNA GGNRATSGGL
FGVEYWRVIL DEAHMIKNRA SKTAKACYEI AATHRWVLTG TPIVNRLEDL FSLVRFLRVE
PWSNFSFWKT FITAPFEKGD FVRALDVVQT VLEPLVLRRT KDMRTPDGEA LVPLPQKTVT
VEKLKFSDPE HDVYRHIFHR AKTTFNANVE AGTLMKSYTT IFAQILRLRQ SCCHPVLTRN
KNIVAEEEDA AAAVDLANGL ADDMDLAALL AKFEADEGET DAATYGAHVL KQIQDEADME
CPICFEEPME EQAVTGCWHS ACKKCLLDYI EQQAAKGELP RCFSCREPIN ARDVFEVIKH
DDDDDDQPDG ADILNAAIQT DEDQEDDEMY TSTQDKVRTI SRKKPRISLR RVNQLSSAKI
STLTTTLKSL KKREPTTKSV VFSQFTSFLD LLAPALTNSS ISWLRFDGSM SQKERAKVLA
EFAERPKFTI LLLSLRAGGV GLNLTCARRV FMMDPWWSFA VEAQAIDRVH RMGQTHDVEV
IRYVVEGTIE EKMLRVQERK KFIASSLGMM SEEEKKMQRI EDIRELLS
//
