ID M3HCB1_LEPIR Unreviewed; 976 AA.
AC M3HCB1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Methyl-accepting chemotaxis protein signaling domain protein {ECO:0000313|EMBL:EMG10330.1};
GN ORFNames=LEP1GSC151_2925 {ECO:0000313|EMBL:EMG10330.1};
OS Leptospira interrogans serovar Grippotyphosa str. LT2186.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1001599 {ECO:0000313|EMBL:EMG10330.1, ECO:0000313|Proteomes:UP000011776};
RN [1] {ECO:0000313|EMBL:EMG10330.1, ECO:0000313|Proteomes:UP000011776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2186 {ECO:0000313|EMBL:EMG10330.1,
RC ECO:0000313|Proteomes:UP000011776};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Tulsiani S.M., Graham G.C., Burns M.-A.,
RA Dohnt M.F., Smythe L.D., McKay D.B., Craig S.B., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMG10330.1}.
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DR EMBL; AFME02000259; EMG10330.1; -; Genomic_DNA.
DR AlphaFoldDB; M3HCB1; -.
DR BioCyc; LINT1001599:G11K9-310-MONOMER; -.
DR Proteomes; UP000011776; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF18947; HAMP_2; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF13188; PAS_8; 2.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00283; MA; 1.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 641..693
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 698..913
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 713..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 72..99
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 884..922
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 976 AA; 108425 MW; 6A07ED2FE152660B CRC64;
MFRKNLGIWI GLAITINGFV FLSIQNFRGP NPSTETNFEE QLQSVQHSSE SFLKTEESIS
EFLLYLSLGK EKETLVSSLE EIEKNLKNLR SSFSESDRKK NPAILKFDKK IGTLFSSIEE
LKEKIYRSKD LKKDTSLFLK SDFFTDLSSF RRTRLEAVKE LSNSVETASV TVVSSTPTEI
QFLVTILEYS GISILLISFL WWSNRSNQRT ILNLEMEFLR MRTAVDNVTT NIMMADRNFN
IVYMNKAIQM MFNKAESDIK KQLSNFNLSN LMGTNIDSFH KNPAHQRGLL DKLSDTFRSS
ITIGGREFDL IANPIVDVNG NKLGTVVEWS DVTEQNKIQK QRKLENEELT RVKVALDNVT
TNIMMADRNL NVVYMNKSIR AMFHSAEDDI KKQFNNFDPS RLIGTNIDIF HKNPAYQRGL
LDKLTDTFRS SINIGGRTFN LIANPIIDET GDRLGSVVEW SDVTEQNKIA EQRKIENEEL
IRVKVALDNT STNIMIADNE FNIRYMNQAV VKMFETGEGD IKKQFAHFNL KSLVGSNIDQ
FHKNPAHQRG VLSSFTGIHK ATIKIGGRTF DLIANPILDT NGKRLGSVVE WSDVTNELAV
QEEVEGIVSA AAKGNFTTRI SLDSKTGFFL NLSRSLNQLL EVSNRGLNEV VEALERISSG
DLTQKITNEY HGTFGKLKEY SNITMDKLSE IIGDIIVRSS SLVTSASEVS STANSLSQGA
SEQAASVEET TSSLEEMTAS IDQNAQNSRQ TEQISSKSSQ DAEEGGASVI ETVKAMKQIA
EKISIIEDIA YQTNLLALNA AIEAARAGDH GKGFAVVASE VRKLAERSQK SANEISSLAG
NSVAIAEKAG NLISQIVPSI RKTADLVQEI TAASDEQSSG VSEINKAMGQ LDQVSQQNAS
ASEELAAISE EMNAQAEQLK ESVLFFKISD GDKRLTNGGG LLHRDFSGTG IIKATPTTRK
DLPKGISPIT EKFERY
//
