ID   M3NBX4_HELPX            Unreviewed;       565 AA.
AC   M3NBX4;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Methyl-accepting chemotaxis protein signaling domain protein {ECO:0000313|EMBL:EMG93151.1};
GN   ORFNames=HMPREF1399_00914 {ECO:0000313|EMBL:EMG93151.1};
OS   Helicobacter pylori GAM118Bi.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=1159027 {ECO:0000313|EMBL:EMG93151.1, ECO:0000313|Proteomes:UP000011879};
RN   [1] {ECO:0000313|EMBL:EMG93151.1, ECO:0000313|Proteomes:UP000011879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GAM118Bi {ECO:0000313|EMBL:EMG93151.1,
RC   ECO:0000313|Proteomes:UP000011879};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Antonio M., Secka O.,
RA   Thomas J., Warren W., Mitreva M., Mardis E.R., Wilson R.K.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMG93151.1}.
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DR   EMBL; APDD01000055; EMG93151.1; -; Genomic_DNA.
DR   RefSeq; WP_001935347.1; NZ_KB644483.1.
DR   AlphaFoldDB; M3NBX4; -.
DR   PATRIC; fig|1159027.3.peg.863; -.
DR   HOGENOM; CLU_000445_107_21_7; -.
DR   Proteomes; UP000011879; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR033480; sCache_2.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF17200; sCache_2; 1.
DR   SMART; SM01049; Cache_2; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        212..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          233..288
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          286..550
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   565 AA;  62484 MW;  7DADD0E24C452B66 CRC64;
     MMFASVFASL GTRIMFVVLA ALLGLGGLFI GFVKVMQKDV LAQLMEHLET GQYKKREKTL
     AYMTKLLEQG IHGYYKNFDN ATARKMALDY FKRINDDKGM IYMVVVDKNG VVLFDPVNPK
     TVGQSGLDLQ SVDGVYYVRG YLEAAKKGGG YTYYKMPKYD GGVPEKKFAY SHYDEVSQMV
     IAATSYYTDI NTENQAITEG VGKVFNENTA KLFLWILTAT IALVVLTLIY AKLRIVKRID
     ELVLKINAFS HGDKDLRARI DVGDRNDEIS QVGRGVNLFV ENARLIMEEI KGISTSNKTS
     MDKLVQIAQE TQKSMKDSST TLNSVKNKAT DVASMMNASI EQSQGLRKRL IETQGLVKES
     KDAIGDLFSQ IIESAHTEEE LSSQVEQLSR NADDVKSILD IINDIADQTN LLALNAAIEA
     ARAGEHGRGF AVVADEVRNL AGRTQKSLAE INSTIMVIVQ EINAVSSQMN LNSQKMERLS
     DMSKSVQETY EKMSSNLSSV VSDSNQSMDD YAKSGRQIEA MVSDFVGVEK VASKTLADSS
     DILNIATHVS GTTMNLDKQV NLFKT
//