ID   M3NMK8_HELPX            Unreviewed;       275 AA.
AC   M3NMK8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   28-JUN-2023, entry version 28.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EMG97565.1};
GN   ORFNames=HMPREF1402_01312 {ECO:0000313|EMBL:EMG97565.1};
OS   Helicobacter pylori GAM121Aii.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=1159030 {ECO:0000313|EMBL:EMG97565.1, ECO:0000313|Proteomes:UP000011875};
RN   [1] {ECO:0000313|EMBL:EMG97565.1, ECO:0000313|Proteomes:UP000011875}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GAM121Aii {ECO:0000313|EMBL:EMG97565.1,
RC   ECO:0000313|Proteomes:UP000011875};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Antonio M., Secka O.,
RA   Thomas J., Warren W., Mitreva M., Mardis E.R., Wilson R.K.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMG97565.1}.
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DR   EMBL; APDG01000062; EMG97565.1; -; Genomic_DNA.
DR   RefSeq; WP_000643485.1; NZ_KB636375.1.
DR   AlphaFoldDB; M3NMK8; -.
DR   PATRIC; fig|1159030.3.peg.1233; -.
DR   HOGENOM; CLU_055968_2_0_7; -.
DR   Proteomes; UP000011875; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          1..275
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   275 AA;  30499 MW;  F7FD55B7C9733DE7 CRC64;
     MKAGIIGLGL MGGSLGLALQ EWGRFKSVIG YDHNALHAKL ALTLGLVDEC VEFEKILECD
     VIFLAIPVEG IIECLKKMTP IKKSATIIDL GGAKAQILHN IPKSIRQNFI AAHPMCGTEF
     YGPKASVKGL YENALVILCD LEDSGTKQVE LAKEIFLGIK ARLIKMKSNE HDTHVAYISH
     LPHVLSYALA NSVLKQNDPE MILSLAGGGF RDMSRLSKSS PLMWKDIFKQ NRDNVLEAIE
     KCEKEIAQAK AWIENNDYES LAEWMAQANK LQEFM
//