ID M3VWP6_FELCA Unreviewed; 1797 AA.
AC M3VWP6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Collagen type XIV alpha 1 chain {ECO:0000313|Ensembl:ENSFCAP00000001357.6};
GN Name=COL14A1 {ECO:0000313|Ensembl:ENSFCAP00000001357.6,
GN ECO:0000313|VGNC:VGNC:82364};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000001357.6, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000001357.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001357.6,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000001357.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001357.6,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000001357.6}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001357.6};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04003518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006943422.1; XM_006943360.3.
DR RefSeq; XP_006943423.1; XM_006943361.3.
DR RefSeq; XP_019678631.1; XM_019823072.1.
DR STRING; 9685.ENSFCAP00000001357; -.
DR PaxDb; 9685-ENSFCAP00000001357; -.
DR Ensembl; ENSFCAT00000001462.6; ENSFCAP00000001357.6; ENSFCAG00000001462.6.
DR GeneID; 101098925; -.
DR KEGG; fca:101098925; -.
DR CTD; 7373; -.
DR VGNC; VGNC:82364; COL14A1.
DR eggNOG; KOG3544; Eukaryota.
DR GeneTree; ENSGT00940000153769; -.
DR HOGENOM; CLU_002527_2_0_1; -.
DR InParanoid; M3VWP6; -.
DR OMA; REMQSDX; -.
DR OrthoDB; 5353225at2759; -.
DR Proteomes; UP000011712; Chromosome F2.
DR Bgee; ENSFCAG00000001462; Expressed in eyeball of camera-type eye and 10 other cell types or tissues.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005614; C:interstitial matrix; IBA:GO_Central.
DR GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR GO; GO:0061050; P:regulation of cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR GO; GO:0003229; P:ventricular cardiac muscle tissue development; IEA:Ensembl.
DR CDD; cd00063; FN3; 8.
DR CDD; cd01482; vWA_collagen_alphaI-XII-like; 2.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR048287; TSPN-like_N.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF15; COLLAGEN ALPHA-1(XIV) CHAIN; 1.
DR Pfam; PF01391; Collagen; 4.
DR Pfam; PF00041; fn3; 8.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00060; FN3; 8.
DR SMART; SM00210; TSPN; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 5.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50853; FN3; 7.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Collagen {ECO:0000256|ARBA:ARBA00023119};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 32..122
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 159..331
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 356..445
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 446..537
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 538..627
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 628..716
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 738..831
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 832..922
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1033..1206
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 126..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1463..1612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1646..1783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1562..1576
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1659..1676
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1711..1748
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1797 AA; 193330 MW; 48CD6A679AC39A3F CRC64;
MKIFQCDMRY WLFPAFLAIA YFCTIVQGQV APPTRLRYNV LSQDSIQISW KAPRGKFGGY
KLLVTPASGG KTNQLNLQNT ATKAIIQGLM PDQNYTVQII AYNKDKESKP AQGQFRIKDL
EKRKDPKPRV KIVDKGNGNK PSPPEEEVKF FCETPAIADI VILVDGSWSI GRFNFRLVRL
FLENLVTAFN VGSEKTRIGL AQYSGDPRIE WHLNAFSTKD EVIEAVRNLP YKGGNTLTGL
ALNYIFENSF KPEAGARTGV SKIGILITDG KSQDDIIPPS RNLRESGVEL FAIGVKNADE
NELREIASEP DSTHVYNVAE FDLMHTVVES LTRTVCSRVE EQDREIKASA LATIGPPTQL
ITSEVTARSF MVNWTHAPGK VEKYRVVYYP ARGGKPDEVV VDGSVSSTVL KNLMSLTEYQ
IAVFAIYAHT ASEGLRGTET TLALPMASDL ELYDVTENSL RVKWNAVPGA SGYLILYAPL
TEGLAGDEKE MKIGETHTDI ELSGLLPNTE YTVTVYAMFG EEASDPVTGQ ETTLPLSPPR
NLRISNVGSN SARLAWDPAS RKVTGYRIVY NNADGTEINE VEVDPVTTFP LKGLTPLTEY
TVAIFSIYDE GQSEPLTGIF TTEEVPAQQY LEIDEVTTDS FRVTWHPLSA DEGQHKLMWI
PVYGGNTEEV ILKEDQDSHV IEGLEPGTEY EVSLLAVLDD GSESEVVTAV GTTLDSIWPE
PATTIIPTRP VTTVFRTGIR NLVVDDETTS SLRVKWDISD SSVQQFRVTY LTAQGDHAEE
VVGTVMVAGS QNNVLLKPLL PNTEYKVTVT PIYDDGEGVS VSAPGKTLPP SGPQNFRVSE
EWYNRLRITW DPPSSPAKGY RIVYKPVSVA GPTLETFVGS GINTILITNL LSGMDYNVKI
FASQASGFSD ALTGVVKTLF LGVTNLQAEQ VQMTSLCARW QVHRHATAYR VVIESLQDTK
KQESTVGGGT TRHCFYGLQP DSEYKISVYT KLQEIEGPSV SIMEKTQSLP TQPPTFPPTI
PPAKEVCRAA KADLVFMVDG SWSIGDENFN KIINFLYSTV GALNKIGADG TQVAIVQFTD
DPRTEFKLNA YQTKETLLDA IKHISYKGGN TKTGKAIKHV RDSLFTAESG TRRGIPKVIV
VITDGRSQDD VNKISGEMQS NGYSIFAVGV ADADYSELVS IGSKPSSRHV FFVDDFDAFK
KIEDELITFV CETASATCPL VFKDGIDLAG FKMMEMFGLV EKDFSSVEGV SMEPGTFNVY
PCYRIHKDAL VSQPTKYLHP EGLPSDYTMS FLFRILPDTP EEPFALWEIL NKNSDPLVGV
ILDNGGKTLT YFNYDYSGDF QTVTFEGPEI RKIFHGSFHK IHIVVSKTLV QVVIDCKHVA
EKAINASANI TLDGVEVLGR MVRSRGPNGN SAPFQLQMFD IICSTSWANK DKCCELPGLR
DEETCPELPH SCSCSEVNTG TLGPAGPPGG PGLRGPKGQR GDQGPKGPEG PRGEIGLPGP
QGPPGPQGPS GLSIQGMPGM PGAKGEKGET GLPGPQGIPG GIGSPGRDGS PGQRGFPGKD
GSSGPPGPPG PIGIPGAPGV PGITGSMGPQ GALGPPGIPG AKGERGERGD LQSQAMVRAV
ARQVCEQLIQ SHMARYTAIL NQIPSHSSSV RTIQGPPGEP GRPGSPGAPG EQGPPGTPGF
PGNAGVPGTP GERGLTGIKG EKGNPGIGTQ GPRGPPGPAG PSGESRPGSP GPPGSPGPRG
PPGHLGVPGP QGPSGQPGYC DPSSCSAYGV GAPHPDQPEF TPVQDELEAM ELWGSGI
//
