ID M3W357_FELCA Unreviewed; 254 AA.
AC M3W357;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=GBD/FH3 domain-containing protein {ECO:0000259|PROSITE:PS51232};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000004569.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000004569.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000004569.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000004569.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000004569.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000004569.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000004569.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04004659; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3W357; -.
DR STRING; 9685.ENSFCAP00000004569; -.
DR Ensembl; ENSFCAT00000004941.6; ENSFCAP00000004569.5; ENSFCAG00000004939.6.
DR eggNOG; KOG1922; Eukaryota.
DR GeneTree; ENSGT00940000155691; -.
DR HOGENOM; CLU_005383_1_0_1; -.
DR InParanoid; M3W357; -.
DR OMA; GIHFIID; -.
DR Proteomes; UP000011712; Chromosome B3.
DR Bgee; ENSFCAG00000004939; Expressed in prefrontal cortex and 10 other cell types or tissues.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR InterPro; IPR027649; Inf2.
DR PANTHER; PTHR46345; INVERTED FORMIN-2; 1.
DR PANTHER; PTHR46345:SF5; INVERTED FORMIN-2; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 1..254
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT REGION 218..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 254 AA; 27778 MW; 04D70A403FE5E115 CRC64;
MSVKEGAQRK WAALKEKLGA QDSDPTEANL ESADPELCIR LLQMPSVVNY SGLRKRLESS
DGGWMVQFLE QSGLDLLLEA LARLSGRGVA RIADALLQLT CISCVRAVLN SQRGIEYILS
NQAYVRQLSL ALDTSNVMVK KQVFELLAAL CIYSPEGHML TLDALDHYKT VCSQQYRFSV
IMNELSDSDN VPYVVTLLSV INAIILGPED LRTRTQLRGE FTGNHPPPAQ GPQRKALGSR
PPPAPLGGLG ASRC
//
