ID M3W3F4_FELCA Unreviewed; 873 AA.
AC M3W3F4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Protein phosphatase 6 regulatory subunit 3 {ECO:0000313|Ensembl:ENSFCAP00000004709.5};
GN Name=PPP6R3 {ECO:0000313|Ensembl:ENSFCAP00000004709.5,
GN ECO:0000313|VGNC:VGNC:64334};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000004709.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000004709.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000004709.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000004709.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000004709.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000004709.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000004709.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SAPS family.
CC {ECO:0000256|ARBA:ARBA00006180}.
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DR EMBL; AANG04000779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003993761.1; XM_003993712.4.
DR AlphaFoldDB; M3W3F4; -.
DR Ensembl; ENSFCAT00000005084.6; ENSFCAP00000004709.5; ENSFCAG00000005076.6.
DR GeneID; 101094955; -.
DR KEGG; fca:101094955; -.
DR CTD; 55291; -.
DR VGNC; VGNC:64334; PPP6R3.
DR GeneTree; ENSGT00390000009899; -.
DR HOGENOM; CLU_012598_0_0_1; -.
DR OrthoDB; 5491840at2759; -.
DR Proteomes; UP000011712; Chromosome D1.
DR Bgee; ENSFCAG00000005076; Expressed in embryonic head and 10 other cell types or tissues.
DR GO; GO:0019903; F:protein phosphatase binding; IEA:InterPro.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR007587; SAPS.
DR PANTHER; PTHR12634:SF12; SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY SUBUNIT 3; 1.
DR PANTHER; PTHR12634; SIT4 YEAST -ASSOCIATING PROTEIN-RELATED; 1.
DR Pfam; PF04499; SAPS; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT REGION 628..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..873
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 873 AA; 97550 MW; AB936BE0D771DCD1 CRC64;
MFWKFDLHSS SHIDTLLERE DVTLKELMDE EDVLQECKAQ NRKLIEFLLK AECLEDLVSF
IIEEPPQDMD EKIRYKYPNI SCELLTSDVS QMNDRLGEDE SLLMKLYSFL LNDSPLNPLL
ASFFSKVLSI LISRKPEQIV DFLKKKRDFV DLIIKHIGTS AIMDLLLRLL TCIEPPQPRQ
DVLNWLNEEQ IIQRLVEIVH PSQEEDRHSN ASQSLCEIVR LSRDQMLQIQ NSSEPDPLLA
TLEKQEIIEQ LLSNIFHKEK NESAIVSAIQ ILLTLLETRR PTFEGHIEIC PPGMSHSACS
VNKSVLEAIR GRLGSFHELL LEPPKKSVMK TTWGVLDPPV GNTRLNVIRL ISSLLQTNTS
SINGDLMELN SVGVILDMFF KYTWNNFLHT QVEICIALIL ASPFENTENN TITDQDSAGD
NLLLKHLFQK CQLIERILDA WEMNEKKQAE GGRRHGYMGH LTRIANCIVH STDKGPNSAL
VQQLIKGLPD TVRERWEAFC ASSLGETNKR NTVDLVTTCH IHSSSDDEID FKETGFSQDS
SLQQAFSDYQ MQQMTSNFID QFGFNDEKFA DQDDIGNVSF DRVSDINFTL NTNESGNIAL
FEACCKERIQ QFDDGGSDEE DIWEEKHIAF APESQRRSSS GSTDSEESTD SEEEDGAKQD
LFEPSGASTE DKMEVDLNEP PNWSANFDVP METTHGAPLD SVGSDVWSTE EPMPTKETGW
ASFSEFTSSL STKDSLRSNS PVEMETSTEP MDPLAPSVAA LGVQPEAPGS VAMEASSDGE
EDTESSDKVT ETVMNGGMKE TLSLTVDAKT ETAVFKSEEG KLSTSQDAAC KDVEESPETA
EAKSAGPRPP SSSPEQRTDQ PSTPGDTSVN GPV
//
