ID M3W7N4_FELCA Unreviewed; 319 AA.
AC M3W7N4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=V-set and transmembrane domain containing 4 {ECO:0000313|Ensembl:ENSFCAP00000006858.5};
GN Name=VSTM4 {ECO:0000313|Ensembl:ENSFCAP00000006858.5,
GN ECO:0000313|VGNC:VGNC:66984};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000006858.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000006858.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000006858.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000006858.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000006858.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000006858.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000006858.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04000273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3W7N4; -.
DR Ensembl; ENSFCAT00000007397.6; ENSFCAP00000006858.5; ENSFCAG00000007396.6.
DR VGNC; VGNC:66984; VSTM4.
DR eggNOG; ENOG502QUVT; Eukaryota.
DR GeneTree; ENSGT00390000008566; -.
DR HOGENOM; CLU_060467_0_0_1; -.
DR OMA; DFCLAIN; -.
DR OrthoDB; 4245862at2759; -.
DR Proteomes; UP000011712; Chromosome D2.
DR Bgee; ENSFCAG00000007396; Expressed in eyeball of camera-type eye and 11 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12207; V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12207:SF8; V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF07686; V-set; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..319
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016316744"
FT TRANSMEM 176..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..154
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 319 AA; 35886 MW; B88BCCA6D101FAA6 CRC64;
MRLLALAAAV LLARAPAPEV CGALNVTVSP GPVVDYLEGE NATLLCHVSQ KRRKDSLLAV
RWFFARPNSQ EALMVKMTKL RVVQYYGNYS RSAFRQRLCL LEERRGALYT LSVLTLRPAD
QGHYVCKVQE ISKHRNKWTA WSNGSSATEM RVISLKASED SSFEKKKETW AFFEDIYIYA
VLVCCVGILS VLLFTLTIIW QSVFSKRKSR VRHYLVKCPQ NSSGETVTSV TSLAPLQPKK
GKRRKEKADV PPAVPAKAPI AATFHKPKLL KPQRKVTLPK IAEENLTYAE LELVKPHRAA
KGLPTSTVYA QILFEENKL
//
