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Database: UniProt
Entry: M3WE92_FELCA
LinkDB: M3WE92_FELCA
Original site: M3WE92_FELCA 
ID   M3WE92_FELCA            Unreviewed;      3940 AA.
AC   M3WE92;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   30-AUG-2017, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000010183};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
OC   Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010183, ECO:0000313|Proteomes:UP000011712};
RN   [1] {ECO:0000313|Ensembl:ENSFCAP00000010183, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010183,
RC   ECO:0000313|Proteomes:UP000011712};
RX   PubMed=17975172; DOI=10.1101/gr.6380007;
RA   Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA   Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
RA   Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
RA   Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
RA   Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
RT   "Initial sequence and comparative analysis of the cat genome.";
RL   Genome Res. 17:1675-1689(2007).
RN   [2] {ECO:0000313|Ensembl:ENSFCAP00000010183}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010183};
RA   Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT   "Sequence assembly of the Felis catus genome version 6.2.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSFCAP00000010183}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010183};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSFCAP00000010183}.
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DR   EMBL; AANG02195383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG02195393; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9685.ENSFCAP00000010183; -.
DR   Ensembl; ENSFCAT00000010964; ENSFCAP00000010183; ENSFCAG00000010961.
DR   eggNOG; KOG2243; Eukaryota.
DR   eggNOG; ENOG410YCNW; LUCA.
DR   GeneTree; ENSGT00760000119152; -.
DR   InParanoid; M3WE92; -.
DR   OMA; EHMPNDT; -.
DR   OrthoDB; EOG091G00T0; -.
DR   Proteomes; UP000011712; Chromosome D2.
DR   Bgee; ENSFCAG00000010961; -.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IBA:GO_Central.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000011712};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT   DOMAIN        7     62       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       69    114       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      122    177       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      183    240       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      248    305       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      499    709       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      925   1122       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1237   1462       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   3940 AA;  446037 MW;  C7D33DED4F244715 CRC64;
     TAQGGGHRTL LYGHAILLRH SYSGMYLCCL STSRSSTDKL AFDVGLQEDT TGEACWWTIH
     PASKQRSEGE KVRVGDDLIL VSVSSERYLH LSYGNGSLHV DAAFQQTLWS VAPISSGSEA
     AQGYLIGGDV LRLLHGHMDE CLTVPSGEHG EEQRRTVHYE GGAVSVHARS LWRLETLRVA
     WSGSHIRWGQ PFRLRHVTTG KYLSLMEDKN LLLMDKEKAD VKSTAFTFRS SKEKLDVGVR
     KEVDGMGTSE IKYGDSVCYI QHINTGLWLT YQSVDVKSVR MGSIQRKAIM HHEGHMDDGL
     NLSRSQHEES RTARVIRSTV FLFNRFIRGL DALSKKVKAS TVDLPIESVS LSLQDLIGYF
     HPPDEHLEHE DKQNRLRALK NRQNLFQEES TWNIFCEPLC LLMVEYSCDQ FLNLAVNLAR
     ARGEAWKSIL NSLYELLAAL IRGNRKNCAQ FSGSLDWLIS RLERLEASSG ILEVLHCVLV
     ESPEALNIIK EGHIKSIISL LDKHGRNHKV LDVLCSLCVC HGVAVRSNQH LICDNLLPGR
     DLLLQTRLVN HVSSMRPNIF LGVSEGSAQY KKWYYELMVD HTEPFVTAEA THLRVGWAST
     EGYSPYPGGG EEWGGNGVGD DLFSYGFDGL HLWSGCIART VSSPNQHLLR TDDVISCCLD
     LSAPSISFRI NGQPVQGMFE NFNIDGLFFP VVSFSAGIKV RFLLGGRHGE FKFLPPPGYA
     PCYEAVLPKE KLKVEHSREY KQERTYTRDL LGPTVSLTQA AFTPIPVDTS QIVLPPHLER
     IREKLAENIH ELWVMNKIEL GWQYGPVRDD NKRQHPCLVE FSKLPEQERN YNLQMSLETL
     KTLLALGCHV GIADEHAEEK VKKMKLPKNY QLTSGYKPAP MDLSFIKLTP SQEAMVDKLA
     ENAHNVWARD RIRQGWTYGI QQDVKNRRNP RLVPYTLLDD RTKKSNKDSL REAVRTLLGY
     GYHLEAPDQD HAARAEVCSG TGERFRIFRA EKTYAVKAGR WYFEFEAVTA GDMRVGWSRP
     GCQPDQELGS DERAFAFDGF KAQRWHQGNE HYGRSWQAGD VVGCMVDMTE HTMMFTLNGE
     ILLDDSGSEL AFKDFDVGDG FIPVCSLGVA QVGRMNFGKD VSTLKYFTIC GLQEGYEPFA
     VNTNRDITMW LSKRLPQFLQ VPSNHEHIEV TRIDGTIDSS PCLKVTQKSF GAQNSTADIM
     FYRLSMPIEC AEVFSKTVAG GLPGAGLFGP KNDLEDYDAD SDFEVLMKTA HGHLVPDRVD
     KDKEATKPEF NNHKDYAQEK PSRLKQRFLL RRTKPDYSTS HSARLTEDVL ADDRDDYDYL
     MQTSTYYYSV RIFPGQEPAN VWVGWITSDF HQYDTGFDLD RVRTVTVTLG DEKGKVHESI
     KRSNCYMVCA GESMSPGQGR NNNGLEIGCV VDAASGLLTF TANGKELSTY YQVEPSTKLF
     PAAFAQATSP NVFQFELGRI KNVMPLSAGL FKSEHKNPVP QCPPRLHVQF LSHVLWSRMP
     NQFLKVDVSR ISERQGWLVQ CLDPLQFMSL HIPEENRSVD ILELTEQEEL LKFHYHTLRL
     YSAVCALGNH RVAHALCSHV DEPQLLYAIE NKYMPGLLRA GYYDLLIDIH LSSYATARLM
     MNSEFIVPMT EETKSITLFP DENKKHGLPG IGLSTSLRPR IQFSSPSFVS INNDCYQYSP
     EFPLDILKAK TIQMLTEAVK EGSLHARDPV GGTTEFLFVP LIKLFYTLLI MGIFHNEDLK
     HILQLIEPSV FKEAATPEED TEALEKEPSM EDSKPEGAGE EEAKGGKRPK EGLLQMKLPE
     PVKLQMCLLL QYLCDCQVRH RIEAIVAFSD DFVAKLQDNQ RFRYNEVMQA LNMSAALTAR
     KTKEFRSPPQ EQINMLLNFK DDKSECPCPE EIRDQLLDFH EDLMTHCGIE LDEDGSLDGN
     SDLTIRGRLL SLVEKVTYLK KKQAEKPVES GSKKSSTLQQ LISETMVRWA QESVIEDPEL
     VRAMFVLLHR QYDGIGGLVR ALPKTYTING VSVEDTINLL ASLGQIRSLL SVRMGKEEEK
     LMIRGLGDIM NNKVFYQHPN LMRALGMHET VMEVMVNVLG GGESKEITFP KMVANCCRFL
     CYFCRISRQN QKAMFDHLSY LLENSSVGLA SPAMRGSTPL DVAAASVMDN NELALALREP
     DLEKVVRYLA GCGLQSCPML VSKGYPDIGW NPVEGERYLD FLRFAVFCNG ESVEENANVV
     VRLLIRRPEC FGPALRGEGG NGLLAAMEEA IKIAEDPSRD GPSPTSGSSK TLETEEEEDD
     TIHMGNAIMT FYAALIDLLG RCAPEMHLIH AGKGEAIRIR SILRSLIPLG DLVGVISIAF
     QMPTIAKDGN VVEPDMSAGF CPDHKAAMVL FLDRVYGIEV QDFLLHLLEV GFLPDLRAAA
     SLDTAALSAT DMALALNRYL CTAVLPLLTR CAPLFAGTEH HASLIDSLLH TVYRLSKGCS
     LTKAQRDSIE VCLLSICGQL RPSMMQHLLR RLVFDVPLLN EHAKMPLKLL TNHYERCWKY
     YCLPGGWGNF GAASEEELHL SRKLFWGIFD ALSQKKYEQE LFKLALPCLS AVAGALPPDY
     MESNYVSMME KQSSMDSEGN FNPQPVDTSN ITIPEKLEYF INKYAEHSHD KWSMDKLANG
     WIYGEIYSDS SKVQPLMKPY KLLSEKEKEI YRWPIKESLK TMLAWGWRVE RTREGDSMAL
     YNRSRRISQT SQVSVDAAHG YSPRAIDMSN VTLSRDLHAM AEMMAENYHN IWAKKKKMEL
     ESKGGGNHPL LVPYDTLTAK EKAKDREKAQ DILKFLQING YAVSSSRGFK DLELDTPSIE
     KRFAYSFLQQ LIRYVDEAHQ YILEFDGGSR SKAEHFPYEQ EIKFFAKVVL PLIDQYFKNH
     RLYFLSAASR PLCSGGHASN KEKEMVTSLF CKLGVLVRHR ISLFGNDATS IVNCLHILGQ
     TLDARTVMKT GLESVKSALR TFLDNAAEDL EKTMENLKQG QFTHTRNQPK GVTQIINYTT
     VALLPMLSSL FEHIGQHQFG EDLILEDVQV SCYRILTSLY ALGTSKSIYV ERQRSALGEC
     LAAFAGAFPV AFLETHLDKH NIYSIYNTKS SRERAALNLP TNVEDVCPNI PSLEKLMEEI
     VELAESGIRY TQMPHVMEVI LPMLCSYMSR WWEHGPENNP ERAEMCCTAL NSEHMNTLLG
     NILKIIYNNL GIDEGAWMKR LAVFSQPIIN KVKPQLLKTH FLPLMEKLKK KAAMVVSEED
     HLKAEARGDM SEAELLILDE FTTLARDLYA FYPLLIRFVD YNRAKWLKEP NPEAEDLFRM
     VAEVFIYWSK SHNFKREEQN FVVQNEINNM SFLITDTKSK MSKAAVSDQE RKKMKRKGDR
     YSTQTSLIVA ALKRLLPIGL NICAPGDQEL IALAKNRFSM KDTEDEVRDI IRSNIHLQGK
     LEDPAIRWQM ALYKDLPNRT EDTSDPEKTV ERVLDIANVL FHLEQKSTSM HRRYYSLVEH
     PQRSKKAVWH KLLSKQRKRA VVACFRMAPL YNLPRHRAVN LFLQGYEKSW IETEEHYFED
     KLIEDLAKPG ADPPEEEEGT KRVDPLHQLI LLFSRTALTE KCKLEEDFLY MAYADIMAKS
     CHDEEDDDGE EEVKSFEEKE MEKQKLLYQQ ARLHDRGAAE MVLQTISASK GDTGPMVAAT
     LKLGIAILNG GNSTVQQKML DYLKEKKDVG FFQSLAGLMQ SCSVLDLNAF ERQNKAEGLG
     MVTEEGSGEK VLQDDEFTCD LFRFLQLLCE GHNSDFQNYL RTQTGNNTTV NIIISTVDYL
     LRVQESISDF YWYYSGKDVI DEQGQRNFSK AIQVAKQVFN TLTEYIQGPC TGNQQSLAHS
     RLWDAVVGFL HVFAHMQMKL SQDSSQIELL KELMDLQKDM VVMLLSMLEG NVVNGTIGKQ
     MVDMLVESSN NVEMILKFFD MFLKLKDLTS SDTFKEYDPD
//
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