ID M3WEN8_FELCA Unreviewed; 791 AA.
AC M3WEN8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=SH3 domain containing 19 {ECO:0000313|Ensembl:ENSFCAP00000010415.6};
GN Name=SH3D19 {ECO:0000313|Ensembl:ENSFCAP00000010415.6,
GN ECO:0000313|VGNC:VGNC:65105};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010415.6, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000010415.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010415.6,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000010415.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010415.6,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000010415.6}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010415.6};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04001605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WEN8; -.
DR PaxDb; 9685-ENSFCAP00000010415; -.
DR Ensembl; ENSFCAT00000011216.6; ENSFCAP00000010415.6; ENSFCAG00000011212.6.
DR VGNC; VGNC:65105; SH3D19.
DR eggNOG; KOG4225; Eukaryota.
DR GeneTree; ENSGT00940000155694; -.
DR HOGENOM; CLU_015305_2_0_1; -.
DR Proteomes; UP000011712; Chromosome B1.
DR Bgee; ENSFCAG00000011212; Expressed in zone of skin and 11 other cell types or tissues.
DR CDD; cd11814; SH3_Eve1_1; 1.
DR CDD; cd11815; SH3_Eve1_2; 1.
DR CDD; cd11816; SH3_Eve1_3; 1.
DR CDD; cd11818; SH3_Eve1_5; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 4.
DR InterPro; IPR035834; Eve1_SH3_1.
DR InterPro; IPR035835; Eve1_SH3_3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45929; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR Pfam; PF00018; SH3_1; 4.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 5.
DR SUPFAM; SSF50044; SH3-domain; 5.
DR PROSITE; PS50002; SH3; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 414..473
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 497..556
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 573..632
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 664..723
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 732..791
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 22..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..350
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 791 AA; 86561 MW; A67388A4E761B254 CRC64;
MNIMNTERSQ NSVVSRIKAF EGQTNKETSG LSVKPEIVPR TLPPRPAVPS GKPTVAPKPA
ANRASGEWDS WTENRLKVAS WEGLTPHPPP QEVGSIPVTK PELPKKPNAG LIRSVNPEIP
GGGPVAESPD GGKKVPTPAP RPLLPKKSVS LENPSPAALL KPVTIPPRLS VASQAKAFRS
LGEGPSANST VTALQSKPSG DIDLISFDDD VLPTPPGNLV EESVGSEMVL DPFQLPTKAE
PTKERAVQPA PTRKPTVIRI PAKPGKCLQE DPQSPPPLPT EKPIGNTYSV VSGKLSNVDR
TRNLESDHMG QTGGSVRGPP RLPPRPINGK VIPTRQPPPK GAPERPPPPK LSATRASNKK
LPFNRSSSDM DLQKKQSNLA FGLSKAKSQV FKNQDPVLPP RPKPGHPLYR KYMLSVPHGI
ANEDIVSQNP GELSCKRGDV LVMLKQAENN YLECQKGEDI GRVHLSQIKI ITPLDEHLRS
RPNDPSHPSR AQKPVDNSAP HAVVLHDFPA EQVDDLHLTS GEIVYLLEKI DTDWYRGKCR
NQTGIFPANY VKVIIDVPEG GKGKRESMSS HCVKGPRCIA RFEYIGDQKD ELSFSEGEII
ILKEYVNEEW ARGELRDRIG IFPLNFVELM EDHPISGVNI SSTKTPPPKA KKEDSGADSQ
DNSLSGEWCE ALHSFTAETS EDLAFRRGDR ILILEHVDSD WYKGRLHDRE GIFPAVFVRP
CQAEAKSSAL ALKGKKAKAL YDFHGENEDE LSFKAGDIIT ELESVDDDWM SGELMGKSGI
FPKNYVQFQV S
//
